NTB-A/SLAMF6/CD352 Antibody (hsF6.4.20) - BSA Free

Flow Cytometry: NTB-A/SLAMF6/CD352 Antibody (hsF6.4.20) [NBP3-09135] - Separation of lymphocytes stained using anti-CD352 (hsF6.4.20) purified antibody (concentration in sample 0,56 ug/ml, GAM-APC, red-filled) from lymphocytes unstained by primary antibody (GAM APC, black-dashed) in flow cytometry analysis (surface staining).

Flow Cytometry: NTB-A/SLAMF6/CD352 Antibody (hsF6.4.20) [NBP3-09135] - Surface staining pattern of human peripheral whole blood stained using anti-human CD352 (hsF6.4.20) Purified antibody (concentration in sample 0,56 ug/ml, GAM APC).

• Reactivity: Hu
• Applications: Flow, ICC/IF, IP
• Clone: hsF6.4.20
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

NTB-A/SLAMF6/CD352 Antibody (hsF6.4.20) - BSA Free Summary

• Immunogen: NTB-A/SLAMF6/CD352 transfectants
• Specificity: The mouse monoclonal antibody hsF6.4.20 recognizes an extracellular epitope of CD352, a transmembrane glycoprotein expressed on NK, T and B cells.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SLAMF6
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1-12 ug/ml
  • Immunocytochemistry/ Immunofluorescence
  • Immunoprecipitation

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein A purified

Alternate Names for NTB-A/SLAMF6/CD352 Antibody (hsF6.4.20) - BSA Free

• Activating NK receptor
• CD352 antigen
• CD352
• KALIFLJ50657
• Ly108
• NK-T-B-antigen
• NTBA receptor
• NTBA
• NTB-A
• NTB-AMGC104953
• NTBAT- and B-cell antigen
• SF2000
• SLAM family member 6
• SLAMF6

Background

NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SLAMF6