Species: Hu
Applications: Flow, CyTOF-ready
Host: Mouse Monoclonal
Species: Mu
Applications: WB, Flow, CyTOF-ready
Host: Sheep Polyclonal
Species: Hu
Applications: WB
Host: Goat Polyclonal
Species: Hu
Applications: ELISA
Host: Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Mu
Applications: Binding Activity
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: Binding Activity
Description
NTBA (NK-, T-, and B-cell Antigen) is a 60 kD type I transmembrane glycoprotein. It is a member of Ig superfamily belonging to CD2/CD150 subfamily, also known as SLAMF6 (SLAM family member 6), LY108, TCOM, or SF2000. This antigen is expressed on NK cells, T cells (upregulated upon activation), and B cells. NTBA is its own ligand. The homophilic interaction of NTBA is involved in the induction of NK cytotoxicity, CD28 independent T cell costimulation, triggering Th1 cytokines production, and regulation of B cell tolerance. It may play a role in the regulation of autoimmune diseases.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
114836 |
| Alternate Names |
- Activating NK receptor
- CD352 antigen
- KALIFLJ50657
- Ly108
- NK-T-B-antigen
- NTBA receptor
- NTB-AMGC104953
- NTBAT- and B-cell antigen
- SF2000
- SLAM family member 6
|
![Flow Cytometry NTB-A/SLAMF6/CD352 Antibody (292811) [Unconjugated]](http://images.novusbio.com/fullsize2/NTBA_MAB19081_Flow_Cytometry_19908.jpg)
![Flow Cytometry NTB-A/SLAMF6/CD352 Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/NTB-A_AF3986_Flow_Cytometry_8221.jpg)
![Sandwich ELISA NTB-A/SLAMF6/CD352 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/NTB-A-SLAMF6-CD352-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79377-img0001.jpg)
