NAC1 Antibody (PCRP-NACC1-1A8)

Flow Cytometry: NAC1 Antibody (PCRP-NACC1-1A8) [NBP3-07508] - Flow Cytometric Analysis of PFA-fixed HeLa cells. NAC1 Mouse Monoclonal Antibody (PCRP-NAC1-1A8) followed by goat anti- Mouse IgG-CF488 (blue); unstained cells (red).

Protein Array: NAC1 Antibody (PCRP-NACC1-1A8) [NBP3-07508] - Analysis of Protein Array containing more than 19,000 full-length human proteins using NAC1 Mouse Monoclonal Antibody (PCRP-NAC1-1A8).

• Reactivity: Hu
• Applications: Flow, MA
• Clone: PCRP-NACC1-1A8
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 0.2 mg/ml

NAC1 Antibody (PCRP-NACC1-1A8) Summary

• Description: 200ug/ml of antibody purified from Bioreactor Concentrate by Protein A or G. Prepared in 10 mM PBS with 0.05% BSA & 0.05% azide. Also available WITHOUT BSA & azide at 1.0 mg/ml. (NBP3-08833)
  
  Antibody with azide - store at 2 to 8C. Antibody without azide - store at -20 to -80 C.
• Immunogen: Recombinant full-length human NAC1 protein (Uniprot: Q96RE7)
• Localization: Nucleus, Cytoplasm. Distribution in the cytoplasm is dependent on phosphorylation.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: NACC1
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry 1-2 ug/million cells
  • Protein Array
• Application Notes: Optimal dilution for a specific application should be determined.
• Theoretical MW: 57 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 10 mM PBS with 0.05% BSA
• Preservative: 0.05% Sodium Azide
• Concentration: 0.2 mg/ml
• Purity: Protein A or G purified

Alternate Names for NAC1 Antibody (PCRP-NACC1-1A8)

• BEND8
• BTB (POZ) domain containing 14B
• BTB/POZ domain-containing protein 14B
• BTBD14B
• BTBD30
• NAC1
• NAC1BEN domain containing 8
• NAC-1FLJ37383
• NACC1
• nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
• nucleus accumbens-associated protein 1
• transcriptional repressor NAC1

Background

The BTB/POZ gene family shares a conserved BTB/POZ protein-protein interaction motif at the N terminus that mediates homodimer or heterodimer formation. NAC1, a member of this family, has been found to be overexpressed in ovarian cancer. This protein appears to play a critical role in tumorigenesis and in the growth and survival of tumor cells, and Nac1 antibodies are therefore useful for cancer research.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: NACC1
• Uniprot:
  • Q96RE7()
  • Q96RE7()