MUC3 Antibody (MUC3/1154) [Biotin]

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Product Details

Summary
Reactivity Hu, Rt(-)Species Glossary
Applications IHC, IHC-P
Clone
MUC3/1154
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

Order Details

MUC3 Antibody (MUC3/1154) [Biotin] Summary

Immunogen
A synthetic peptide of 35 amino acids, SIB35 (C-HSTPSFTSSITTTETTSHSTPSFTSSITTTETTS), which contains two of the MUC3 tandem repeats, coupled to KLH.
Localization
Cytoplasmic and cell surface
Specificity
It recognizes a protein of HMW, identified as mucin 3 glycoprotein (MUC3). This MAb shows no cross-reaction with human milk fat globule membranes, MUC1, or MUC2. The Mucins are a family of highly glycosylated, secreted proteins with a basic structure consisting of a variable number of tandem repeats (VNTRs) encoded by 60 base pairs (Mucin 1), 69 base pairs (Mucin 2) and 51 base pairs (Mucin 3). The number of repeats is highly polymorphic and varies among different alleles. Mucin 1 proteins are expressed as type I membrane proteins in addition to secreted forms. Mucin 1 is aberrantly expressed in epithelial tumors including breast carcinomas. Mucin 2 coats the epithelia of the intestines and airways and is associated with colonic tumors. Mucin 3 is a major component of various mucus gels and is broadly expressed in normal and tumor cells.
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
MUC3A
Purity
Protein A or G purified
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
Optimal dilution of this antibody should be experimentally determined.
Readout System

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein A or G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for MUC3 Antibody (MUC3/1154) [Biotin]

  • MUC-3A
  • mucin 3, intestinal
  • mucin 3A, cell surface associated
  • mucin 3A, intestinal
  • mucin-3A

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-47687AF350
Alexa Fluor 405 NBP2-47687AF405
Alexa Fluor 488 NBP2-47687AF488
Alexa Fluor 532 NBP2-47687AF532
Alexa Fluor 594 NBP2-47687AF594
Alexa Fluor 647 NBP2-47687AF647
Alexa Fluor 700 NBP2-47687AF700
Alexa Fluor 750 NBP2-47687AF750
Allophycocyanin NBP2-47687APC
Allophycocyanin/Cy7 NBP2-47687APCCY7
Biotin NBP2-47687B
DyLight 350 NBP2-47687UV
DyLight 405 NBP2-47687V
DyLight 488 NBP2-47687G
DyLight 550 NBP2-47687R
DyLight 594 NBP2-47687DL594
DyLight 650 NBP2-47687C
DyLight 680 NBP2-47687FR
DyLight 755 NBP2-47687IR
FITC NBP2-47687F
HRP NBP2-47687H
Janelia Fluor 549 NBP2-47687JF549
Janelia Fluor 646 NBP2-47687JF646
PE NBP2-47687PE
PE/Atto594 NBP2-47687PEATT594
PE/Cy5.5 NBP2-47687PECY55
PE/Cy7 NBP2-47687PECY7
PerCP NBP2-47687PCP

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Array NBP2-47687B

Bioinformatics Tool for MUC3 Antibody (NBP2-47687B)

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Calculators

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Bioinformatics

Gene Symbol MUC3A
Uniprot