mtTFA Antibody (18G102B2E11) [Biotin]

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Product Details

Summary
Reactivity Hu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clone
18G102B2E11
Clonality
Monoclonal
Host
Mouse
Conjugate
Biotin

mtTFA Antibody (18G102B2E11) [Biotin] Summary

Immunogen
Human mtTFA [Swiss-Prot# Q00059]
Localization
Mitochondrion.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TFAM
Purity
Protein G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This mtTFA (18G102B2E11) antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin-embedded sections and Western blot, where a band can be seen around 20 - 25 kDa.
Readout System

Reactivity Notes

Human and rat.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for mtTFA Antibody (18G102B2E11) [Biotin]

  • mitochondrial transcription factor A
  • MtTF1
  • mtTFA
  • TCF-6
  • TCF6L1
  • TCF6L2Mitochondrial transcription factor 1
  • TCF6TCF6L3
  • Transcription factor 6
  • Transcription factor 6-like 2 (mitochondrial transcription factor)
  • Transcription factor 6-like 2
  • transcription factor A, mitochondrial

Background

Mitochondrial transcription factor A (mtTFA) is one of the most important transcription factors related to mitochondrial genes. In turn, mtTFA regulates several pathways for metabolism and energy storage in cells. In several metabolic diseases, including insulin-resistance related diabetes, the activity of mtTFA is directly linked to interactions with oxidative stress and fat cell differentiation. In cancers, mtTFA is important in supporting the energy requirements of the fast-growing cells. When dysfunctions in mitochondrial activity occur, mtTFA and its relationship to other proteins is often to blame; mtTFA is known to interact with TNF-alpha, PPAR, UCP4, POLRMT and others. Increased expression of mtTFA might be a good biomarker for Arsenic-induced Bowen's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for mtTFA Antibody (NBP1-71648B). (Showing 1 - 1 of 1 FAQ).

  1. I have considered to purchase mtTFA Antibody (18G102B2E11) [Biotin] 0.1ml for my research. But, I want to clarify whether this antibody can be applied in IHC for frozen section?
    • Our mtTFA antibody with catalogue number NBP1-71648B has been validated for IHC with paraffin-embedded samples, but has not yet been tested with frozen tissue.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

DyLight 350 Labeled NBP1-71648UV
DyLight 405 Labeled NBP1-71648V
DyLight 488 Labeled NBP1-71648G
DyLight 550 Labeled NBP1-71648R
DyLight 650 Labeled NBP1-71648C
DyLight 680 Labeled NBP1-71648FR
DyLight 755 Labeled NBP1-71648IR
FITC Labeled NBP1-71648F
HRP Labeled NBP1-71648H

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Bioinformatics Tool for mtTFA Antibody (NBP1-71648B)

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Diseases for mtTFA Antibody (NBP1-71648B)

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Research Areas for mtTFA Antibody (NBP1-71648B)

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Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol TFAM