mtTFA Antibody (18G102B2E11) [DyLight 650]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P, KO
Clone
18G102B2E11
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 650

mtTFA Antibody (18G102B2E11) [DyLight 650] Summary

Immunogen
Human mtTFA [Swiss-Prot# Q00059]
Localization
Mitochondrion.
Isotype
IgG2b Kappa
Clonality
Monoclonal
Host
Mouse
Gene
TFAM
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Knockout Validated
Application Notes
This mtTFA (18G102B2E11) antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin-embedded sections and Western blot, where a band can be seen around 20 - 25 kDa.

Reactivity Notes

Human and rat. Mouse reactivity reported in scientific literature (PMID: 28053692)

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for mtTFA Antibody (18G102B2E11) [DyLight 650]

  • mitochondrial transcription factor A
  • MtTF1
  • mtTFA
  • TCF-6
  • TCF6L1
  • TCF6L2Mitochondrial transcription factor 1
  • TCF6TCF6L3
  • Transcription factor 6
  • Transcription factor 6-like 2 (mitochondrial transcription factor)
  • Transcription factor 6-like 2
  • transcription factor A, mitochondrial

Background

Mitochondrial transcription factor A (mtTFA) is one of the most important transcription factors related to mitochondrial genes. In turn, mtTFA regulates several pathways for metabolism and energy storage in cells. In several metabolic diseases, including insulin-resistance related diabetes, the activity of mtTFA is directly linked to interactions with oxidative stress and fat cell differentiation. In cancers, mtTFA is important in supporting the energy requirements of the fast-growing cells. When dysfunctions in mitochondrial activity occur, mtTFA and its relationship to other proteins is often to blame; mtTFA is known to interact with TNF-alpha, PPAR, UCP4, POLRMT and others. Increased expression of mtTFA might be a good biomarker for Arsenic-induced Bowen's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for mtTFA Antibody (NBP1-71648C) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP1-71648AF350
Alexa Fluor 405 NBP1-71648AF405
Alexa Fluor 488 NBP1-71648AF488
Alexa Fluor 532 NBP1-71648AF532
Alexa Fluor 594 NBP1-71648AF594
Alexa Fluor 647 NBP1-71648AF647
Alexa Fluor 700 NBP1-71648AF700
Alexa Fluor 750 NBP1-71648AF750
Biotin NBP1-71648B
DyLight 350 NBP1-71648UV
DyLight 405 NBP1-71648V
DyLight 488 NBP1-71648G
DyLight 550 NBP1-71648R
DyLight 594 NBP1-71648DL594
DyLight 650 NBP1-71648C
DyLight 680 NBP1-71648FR
DyLight 755 NBP1-71648IR
FITC NBP1-71648F
HRP NBP1-71648H
Janelia Fluor 549 NBP1-71648JF549
Janelia Fluor 646 NBP1-71648JF646

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Bioinformatics Tool for mtTFA Antibody (NBP1-71648C)

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Diseases for mtTFA Antibody (NBP1-71648C)

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Blogs on mtTFA

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Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

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Bioinformatics

Gene Symbol TFAM