Mkl1 Antibody (CL4281) - BSA Free

Western Blot: Mkl1 Antibody (CL4281) [NBP2-59047] - Analysis in human cell line HL-60.

Immunohistochemistry-Paraffin: Mkl1 Antibody (CL4281) [NBP2-59047] - Staining of human testis shows moderate nuclear positivity in a subset of cells in seminiferous tubules

Immunohistochemistry-Paraffin: Mkl1 Antibody (CL4281) [NBP2-59047] - Staining of human lymph node shows moderate immunoreactivity in a subset of lymphoid cells.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: CL4281
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: BSA Free

Mkl1 Antibody (CL4281) - BSA Free Summary

• Immunogen: This antibody was developed using a recombinant protein derived from Q969V6, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MRTFA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
  • Western Blot 1 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  Mkl1 Recombinant Protein Antigen (NBP2-59047PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Protein A purified

Alternate Names for Mkl1 Antibody (CL4281) - BSA Free

• AMKL
• KIAA1438
• MALSAP and coiled-coil domain
• megakaryoblastic leukemia (translocation) 1
• Megakaryoblastic leukemia 1 protein
• Megakaryocytic acute leukemia protein
• MKL/myocardin-like protein 1
• Myocardin-related transcription factor A
• RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein

Background

MKL1 (megakaryoblastic leukemia 1 protein) was identified as part of a t(1;22) translocation with RBM15 associated with acute megakaryoblastic leukemia. It is a transcriptional coactivator of serum response factor (SRF) that promotes muscle differentiation and also plays a role in promoting maturation of megakaryocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MRTFA