Mkl1 Antibody (CL4281) [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB, IHC
• Clone: CL4281
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

Mkl1 Antibody (CL4281) [mFluor Violet 450 SE] Summary

• Immunogen: This antibody was generated using a recombinant protein sequence of Q969V6, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: MRTFA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Mkl1 Antibody (CL4281) [mFluor Violet 450 SE]

• AMKL
• KIAA1438
• MALSAP and coiled-coil domain
• megakaryoblastic leukemia (translocation) 1
• Megakaryoblastic leukemia 1 protein
• Megakaryocytic acute leukemia protein
• MKL/myocardin-like protein 1
• Myocardin-related transcription factor A
• RNA-binding motif protein 15/megakaryoblastic leukemia-1 fusion protein

Background

MKL1 (megakaryoblastic leukemia 1 protein) was identified as part of a t(1;22) translocation with RBM15 associated with acute megakaryoblastic leukemia. It is a transcriptional coactivator of serum response factor (SRF) that promotes muscle differentiation and also plays a role in promoting maturation of megakaryocytes.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MRTFA