mGluR3 Antibody (6H10C3) - BSA Free

Images

 
Western Blot: mGluR3 Antibody (6H10C3) [NBP2-61842] - Analysis using GRM3 mAb against HEK293 (1) and GRM3 (AA: extra 433-576)-hIgGFc transfected HEK293 (2) cell lysate.
Immunohistochemistry: mGluR3 Antibody (6H10C3) [NBP2-61842] - Analysis of paraffin-embedded stomach cancer tissues using GRM3 mouse mAb with DAB staining.
Western Blot: mGluR3 Antibody (6H10C3) [NBP2-61842] - Analysis using GRM3 mAb against human GRM3 (AA: extra 433-576) recombinant protein. (Expected MW is 42.4 kDa)
Immunohistochemistry: mGluR3 Antibody (6H10C3) [NBP2-61842] - Analysis of paraffin-embedded bladder cancer tissues using GRM3 mouse mAb with DAB staining.
ELISA: mGluR3 Antibody (6H10C3) [NBP2-61842] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)
ELISA: mGluR3 Antibody (6H10C3) [NBP2-61842] - Analysis of SH-SY5Y cells using GRM3 mouse mAb (green) and negative control (red).

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, IHC, IHC-P
Clone
6H10C3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

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Catalog# & Formulation Size Price

mGluR3 Antibody (6H10C3) - BSA Free Summary

Immunogen
Purified recombinant fragment of human GRM3 (AA: extra 433-576) expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
GRM3
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Flow Cytometry 1:10-1:1000
  • Immunohistochemistry 1:10-1:1000
  • Immunohistochemistry-Paraffin 1:200 - 1:1000
  • Western Blot 1:100-1:2000
Theoretical MW
99 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for mGluR3 Antibody (6H10C3) - BSA Free

  • GLUR3
  • glutamate receptor, metabotropic 3
  • GPRC1C
  • GPRC1Cglutamate metabotropic receptor 3
  • GRM3
  • mGlu3
  • mGluR3
  • MGLUR3metabotropic glutamate receptor 3

Background

L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G protein-coupled receptors, that have been divided into 3 groups on the basis of sequence homology, putative signal transduction mechanisms, and pharmacologic properties. Group I includes GRM1 and GRM5 and these receptors have been shown to activate phospholipase C. Group II includes GRM2 and GRM3 while Group III includes GRM4, GRM6, GRM7 and GRM8. Group II and III receptors are linked to the inhibition of the cyclic AMP cascade but differ in their agonist selectivities.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GRM3