LSD1 Antibody


Western Blot: LSD1 Antibody [NB100-56496] - analysis of LSD1 in Jurkat cell lysate in the 1) absence and 2) presence of immunizing peptide using this antibody.
Immunohistochemistry-Paraffin: LSD1 Antibody [NB100-56496] - analysis of human brain, cortex using this antibody at 10 ug/ml.
Simple Western: LSD1 Antibody [NB100-56496] - Simple Western lane view shows a specific band for LSD1 in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa separation more

Product Details

Reactivity Hu, Mu, Rt, Ca, PmSpecies Glossary
Applications WB, Simple Western, IHC, IHC-P
0.5 mg/ml

Order Details

LSD1 Antibody Summary

A portion of amino acids 800-850 of human LSD1 was used as the immunogen.
Nucleus Marker
The amino acid sequence used as immunogen is 100% homologous in human (isoforms CRA_a,CRA _b and CRA _c), rhesus monkey, dog (isoforms 1 and 2), mouse (isoforms 1, 2, 3 and 4) and rat.
Protein G purified
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Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS containing 0.2% gelatin
0.05% Sodium Azide
0.5 mg/ml
Protein G purified


  • Western Blot 1-3 ug/ml
  • Simple Western 1:10
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 ug/ml
Application Notes
In Simple Western only 10-15 uL of the recommended dilution is used per data point.

Reactivity Notes

Cross reacts with Dog, Human, Mouse, Rat and Rhesus Monkey.

Alternate Names for LSD1 Antibody

  • amine oxidase (flavin containing) domain 2
  • AOF2
  • AOF2lysine-specific histone demethylase 1
  • BHC110
  • BHC110FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit
  • Flavin-containing amine oxidase domain-containing protein 2
  • KIAA0601KDM1
  • LSD1
  • LSD1BRAF35-HDAC complex protein BHC110
  • lysine (K)-specific demethylase 1
  • Lysine (K)specific Demethylase 1A
  • lysine (K)-specific demethylase 1A
  • lysine-specific histone demethylase 1A


LSD1 a recently identified, first known lysine-specific histone demethylase, is an 886 amino acid nuclear protein belonging to flavin monoamine oxidase family. It contains a SWIRM domain, a FAD-binding motif and an amine oxidase domain. This protein is ubiquitously expressed and is a component of several histone deacetylase complexes. LSD1 acts as a component of the CoREST and other transcriptional co-repressor complexes and also plays an important role in silencing neuronal-specific genes in non-neuronal cells. It is also known to demethylate Lys-4 of histone H3, a specific tag for epigenetic transcriptional activation. Reports suggest that it plays an important role in stimulating androgen-receptor-dependent transcription converting oxygen to hydrogen peroxide (might use alternative electron acceptors). Along with nuclear FHL2 it serves as a novel biomarker predictive for prostate cancer.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol KDM1A

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