LSD1 Products

Antibodies
LSD1 Antibody (1B2E5)
LSD1 Antibody (1B2E5)
NB100-1762
Species: Hu, Mu, Pm
Applications: WB, Simple Western, ChIP, ELISA, IHC, IHC-P
Host: Mouse Monoclonal
LSD1 Antibody
LSD1 Antibody
NB100-56475
Species: Hu, Mu, Rt, Ca, Pm, Ze
Applications: WB
Host: Rabbit Polyclonal
LSD1 Antibody
LSD1 Antibody
NB100-56496
Species: Hu, Mu, Rt, Ca, Pm
Applications: WB, Simple Western, IHC, IHC-P
Host: Rabbit Polyclonal
Antibody Pairs
LSD1 Antibody Pair
LSD1 Antibody Pair
H00023028-PW1
Species: Hu
Applications: WB, IP
Kits
LSD1 Fluorometric Assay Kit
LSD1 Fluorometric Assay Kit
KA1603
Applications: Func
LSD1 Assay/Inhibitor Screenin ...
LSD1 Assay/Inhibitor Screening Ass...
KA1525
Applications: Func
LSD1 Assay/Inhibitor Screenin ...
LSD1 Assay/Inhibitor Screening Ass...
KA1548
Applications: Func
Lysates
LSD1 Overexpression Lysate (D ...
LSD1 Overexpression Lysate (Denatu...
H00023028-T01
Species: Hu
Applications: WB
LSD1 Overexpression Lysate (N ...
LSD1 Overexpression Lysate (Native)
NBL1-07573
Applications: WB
Proteins
LSD1 Recombinant Protein
LSD1 Recombinant Protein
H00023028-P01
Species: Hu
Applications: WB, ELISA, PA
LSD1 Recombinant Protein
LSD1 Recombinant Protein
H00023028-Q01
Species: Hu
Applications: WB, ELISA, PA
LSD1 Peptide
LSD1 Peptide
NBP1-76417PEP
Species: Hu
Applications: AC
RNAi
LSD1 RNAi
LSD1 RNAi
H00023028-R01
Species: Hu

Description

LSD1 a recently identified, first known lysine-specific histone demethylase, is an 886 amino acid nuclear protein belonging to flavin monoamine oxidase family. It contains a SWIRM domain, a FAD-binding motif and an amine oxidase domain. This protein is ubiquitously expressed and is a component of several histone deacetylase complexes. LSD1 acts as a component of the CoREST and other transcriptional co-repressor complexes and also plays an important role in silencing neuronal-specific genes in non-neuronal cells. It is also known to demethylate Lys-4 of histone H3, a specific tag for epigenetic transcriptional activation. Reports suggest that it plays an important role in stimulating androgen-receptor-dependent transcription converting oxygen to hydrogen peroxide (might use alternative electron acceptors). Along with nuclear FHL2 it serves as a novel biomarker predictive for prostate cancer.

Bioinformatics

Entrez Human
Mouse
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 23028
Alternate Names
  • lysine (K)-specific demethylase 1
  • lysine-specific histone demethylase 1A
  • amine oxidase (flavin containing) domain 2
  • AOF2lysine-specific histone demethylase 1
  • BHC110FAD-binding protein BRAF35-HDAC complex, 110 kDa subunit
  • LSD1BRAF35-HDAC complex protein BHC110
  • KIAA0601KDM1
  • Flavin-containing amine oxidase domain-containing protein 2
  • lysine (K)-specific demethylase 1A

Research Areas for LSD1

Find related products by research area and learn more about each of the different research areas below.

Chromatin Modifiers
DNA Repair
DNA replication, Transcription, Translation and Splicing
Epigenetics

Bioinformatics Tool for LSD1

Discover related pathways, diseases and genes to LSD1. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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