KCTD11 Antibody

Western Blot: KCTD11 Antibody [NBP1-72049] HEK293 lysate (10ug protein in RIPA buffer) overexpressing Human KCTD11 with DYKDDDDK tag probed with (1.0ug/ml) in Lane A and probed with anti-DYKDDDDK Tag (1/5000) in lane C. Mock-transfected HEK293 probed with (1mg/ml) in Lane B. Primary incubations we

• Reactivity: Hu, Mu, Rt, Bv, Ca
• Applications: WB, ELISA
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: 0.5 mg/ml

KCTD11 Antibody Summary

• Description: Novus Biologicals Goat KCTD11 Antibody (NBP1-72049) is a polyclonal antibody validated for use in WB and ELISA. Anti-KCTD11 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Peptide with sequence C-PEVEYGRLGLQP corresponding to internal region according to NP_001002914.1.
• Predicted Species: Mouse (100%), Rat (100%), Canine (100%), Bovine (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: KCTD11
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:16000
  • Western Blot 1 - 2 ug/ml
• Application Notes: WB: In transfected HEK293 transiently expressing full-length human KCTD11 (myc and DYKDDDDK tagged), a band of approx. 30 kDa band was observed. No bands were observed in mock-transfected HEK293 and the same band was observed using anti-DYKDDDDK tag antibody.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for KCTD11 Antibody

• BTB/POZ domain-containing protein KCTD11
• C17orf36
• chromosome 17 open reading frame 36
• MGC129844
• potassium channel tetramerisation domain containing 11
• REn
• REN/KCTD11
• RENpotassium channel tetramerization domain containing 11
• retinoic acid, EGF, NGF induced gene protein
• retinoic acid, EGF, NGF induced gene/potassium channel tetramerization domaincontaining 11

Background

KCTD11 play a role as a marker and a regulator of neuronal differentiation; Up-regulated by a variety of neurogenicsignals, such as retinoic acid, epidermal growth factor/EGF and NGFB/nerve growth factor. Induces apoptosis, growtharrest and the expression of cyc

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for KCTD11 Antibody (NBP1-72049)(1)

Publication using NBP1-72049

• Di Marcotullio L, Ferretti E, De Smaele E et al. REN(KCTD11) is a suppressor of Hedgehog signaling and is deleted in human medulloblastoma. Proc Natl Acad Sci U S A 2004-07-01 [PMID: 15249678]

Bioinformatics

• Gene Symbol: KCTD11
• Entrez:
  • 147040(Human)
  • 216858(Mouse)
  • 363634(Rat)
• Uniprot:
  • NP_001002914.1(Human)