AGTR-2 Antibody - BSA Free

Images

 
Western Blot: AGTR-2 Antibody [NBP1-77368] - Mouse liver tissue lysate with Angiotensin II Type 2 Receptor antibody at 0.5 ug/ml.
Immunocytochemistry/ Immunofluorescence: AGTR-2 Antibody [NBP1-77368] - Immunofluorescence of AGTR-2 in Jurkat cells with AGTR-2 Antibody.
Immunohistochemistry: AGTR-2 Antibody [NBP1-77368] - Representative immunofluorescent immunohistochemical stained images demonstrating the expression of ATIIR2 [red] on GFAP+ CSCs [green]. Negative control was a GBM ...read more
Immunocytochemistry/ Immunofluorescence: AGTR-2 Antibody [NBP1-77368] - Jurkat cell with AGTR2 Antibody at 5 ug/ml.
Immunohistochemistry-Paraffin: AGTR-2 Antibody [NBP1-77368] - Rat liver tissue with AGTR2 antibody at 5 ug/ml.
Immunohistochemistry-Paraffin: AGTR-2 Antibody [NBP1-77368] - Representative 3,3-diaminobenzidine immunohistochemical stained images demonstrating cytoplasmic expression of SOX2, PRR, by cells within GBM, and the ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Rb, ShSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

AGTR-2 Antibody - BSA Free Summary

Immunogen
AGTR2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR2. The immunogen is located within amino acids 220 - 270 of AGTR2. Amino Acid Squence: LKTNSYGKNRITRDQV
Predicted Species
Sheep (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AGTR2
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1-5 ug/ml
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
  • Western Blot 0.5 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID 27200356).
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
AGTR-2 Protein (NBP1-77368PEP)
Publications
Read Publications using
NBP1-77368 in the following applications:

  • 4 publications
  • IHC
    10 publications
  • 7 publications
  • WB
    5 publications

Reactivity Notes

Use in Rabbit reported in scientific literature (PMID:35372645).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for AGTR-2 Antibody - BSA Free

  • AGTR2
  • AGTR-2
  • Angiostensin Receptor
  • angiotensin II receptor, type 2
  • Angiotensin II type-2 receptor
  • angiotensin receptor 2
  • AT2
  • AT2ATGR2
  • AT2R
  • MRX88
  • MRX88type-2 angiotensin II receptor

Background

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for AGTR-2 Antibody (NBP1-77368)(24)

We have publications tested in 4 confirmed species: Human, Mouse, Rat, Rabbit.

We have publications tested in 4 applications: ICC/IF, IHC, IHC-P, WB.


Filter By Application
ICC/IF
(4)
IHC
(10)
IHC-P
(7)
WB
(5)
All Applications
Filter By Species
Human
(13)
Mouse
(4)
Rat
(2)
Rabbit
(1)
All Species
Showing Publications 1 - 10 of 24. Show All 24 Publications.
Publications using NBP1-77368 Applications Species
Deng Z, Gao X, Utsunomiya H et al. Effects of oral losartan administration on homeostasis of articular cartilage and bone in a rabbit model Bone Reports Jun 1 2022 [PMID: 35372645] (IHC, Rabbit) IHC Rabbit
Munro MJ, Peng L, Wickremesekera SK, Tan ST Colon adenocarcinoma-derived cells possessing stem cell function can be modulated using renin-angiotensin system inhibitors PloS one Aug 24 2021 [PMID: 34428252] (IHC, ICC/IF) IHC, ICC/IF
James NE, Cantillo E, Yano N et al. Expression of Components of the Renin-Angiotensin System by the Putative Stem Cell Population Within WHO Grade I Meningioma Front. Surg. May 16 2019 [PMID: 31157231] (IHC-P, Human) IHC-P Human
Siljee S, Gower A, Brasch H Et al. Expression of Angiotensin II Receptor 2 in Microcystic Lymphatic Malformation Journal of Vascular Anomalies Aug 5 2021 (IHC, Human) IHC Human
Siljee S, Milne B, Brasch H et al. Expression of Components of the Renin-Angiotensin System by Cancer Stem Cells in Renal Clear Cell Carcinoma Biomolecules Apr 7 2021 [PMID: 33916968] (IHC, Human) IHC Human
Siljee S, Buchanan O, Brasch HD, et al. Cancer Stem Cells in Metastatic Head and Neck Cutaneous Squamous Cell Carcinoma Express Components of the Renin-Angiotensin System Cells Jan 27 2021 [PMID: 33513805] (IHC) IHC
Wang X, Tu J, Jiang J et al. Angiotensin II Type 2 Receptor Modulates Synovial Macrophage Polarization by Inhibiting GRK2 Membrane Translocation in a Rat Model of Collagen-Induced Arthritis Cell Mol Neurobiol Nov 2 2020 [PMID: 33148713] (WB, Mouse) WB Mouse
Siljee S, Pilkington T, Brasch HD et al. Cancer Stem Cells in Head and Neck Metastatic Malignant Melanoma Express Components of the Renin-Angiotensin System Cell Mol Neurobiol Nov 2 2020 [PMID: 33147716] (WB, Mouse) WB Mouse
Chen H, Zhu Y, Zhao X Prenatal ethanol exposure increased the susceptibility of adult offspring rats to glomerulosclerosis Toxicol. Lett. Dec 4 2019 [PMID: 31811911] (WB, Rat) WB Rat
Wickremesekera A, Brasch H, Lee V et al. Cancer stem cell subpopulations in metastatic melanoma to the brain express components of the renin-angiotensin system JCMT Aug 27 2019
Show All 24 Publications.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol AGTR2
Uniprot