AGTR-2 Antibody

Images

 
Western Blot: AGTR-2 Antibody [NBP1-77368] - Mouse liver tissue lysate with Angiotensin II Type 2 Receptor antibody at 0.5 ug/ml.
Immunohistochemistry-Paraffin: AGTR-2 Antibody [NBP1-77368] - Rat liver tissue with AGTR2 antibody at 5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Rt, ShSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

AGTR-2 Antibody Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR2. The immunogen is located within amino acids 220 - 270 of AGTR2.
Predicted Species
Sheep (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AGTR2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Application Notes
Use in Immunocytochemistry/immunofluorescence reported in scientific literature (PMID 27200356).
Theoretical MW
40 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
AGTR-2 Peptide (NBP1-77368PEP)
Publications
Read Publications using
NBP1-77368 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for AGTR-2 Antibody

  • AGTR2
  • AGTR-2
  • angiotensin II receptor, type 2
  • Angiotensin II type-2 receptor
  • angiotensin receptor 2
  • AT2
  • AT2ATGR2
  • AT2R
  • MRX88
  • MRX88type-2 angiotensin II receptor

Background

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for AGTR-2 Antibody (NBP1-77368)(10)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 4 applications: ICC/IF, IHC, IHC-P, WB.


Filter By Application
ICC/IF
(1)
IHC
(5)
IHC-P
(3)
WB
(2)
All Applications
Filter By Species
Human
(7)
Mouse
(1)
Rat
(1)
All Species
Showing Publications 1 - 10 of 10.
Publications using NBP1-77368 Applications Species
On N, Koh SP, Brasch HD et al. Embryonic Stem Cell-Like Population in Dupuytren's Disease Expresses Components of the Renin-Angiotensin System Plast Reconstr Surg Glob Open 2017 Jul 01 [PMID: 28831359] (IHC-P, Human) IHC-P Human
Ram RS, Brasch HD, Dunne JC et al. Cancer Stem Cells in Moderately Differentiated Lip Squamous Cell Carcinoma Express Components of the Renin-Angiotensin System. Front Surg. 2017 Jun 21 [PMID: 28634582] (IHC, Human) IHC Human
Featherston T, Yu HH, Dunne JC et al. Cancer Stem Cells in Moderately Differentiated Buccal Mucosal Squamous Cell Carcinoma Express Components of the Renin-Angiotensin System. Front Surg. Oct 12 2016 [PMID: 27730124] (IHC, Human) IHC Human
Bradshaw AR, Wickremesekera AC, Brasch HD et al. Glioblastoma Multiforme Cancer Stem Cells Express Components of the Renin-Angiotensin System. Front Surg. Oct 12 2016 [PMID: 27730123] (IHC, Human) IHC Human
Garnacho-Castano MV, Alva N, Sanchez-Nuno S et al. Hypothermia can reverse hepatic oxidative stress damage induced by hypoxia in rats J. Physiol. Biochem. 2016 Jul 08 [PMID: 27387890] (IHC, Human) IHC Human
Itinteang T, Dunne JC, Chibnall AM et al. Cancer stem cells in moderately differentiated oral tongue squamous cell carcinoma express components of the renin-angiotensin system. J Clin Pathol 2016 Oct [PMID: 27371611] (IHC, Human) IHC Human
Siljee S, Keane E, Marsh R et al. Expression of the Components of the Renin-Angiotensin System in Venous Malformation. Front Surg. May 20 2016 [PMID: 27200356] (IHC-P, ICC/IF, Human) IHC-P, ICC/IF Human
Khajah MA, Fateel MM, Ananthalakshmi KV, Luqmani YA et al. Anti-Inflammatory Action of Angiotensin 1-7 in Experimental Colitis PLoS ONE Mar 11 2016 [PMID: 26963721] (WB, IHC-P, Mouse) WB, IHC-P Mouse
Ao Y, Sun Z, Hu S et al. Low functional programming of renal AT2R mediates the developmental origin of glomerulosclerosis in adult offspring induced by prenatal caffeine exposure. Toxicol. Appl. Pharmacol. 2015 May 15 [PMID: 25986755] (WB, Rat) WB Rat
Hafko R, Villapol S, Nostramo R et al. Commercially available angiotensin II At(2) receptor antibodies are nonspecific. PLoS One 2013 [PMID: 23840911]

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Bioinformatics

Gene Symbol AGTR2
Entrez
Uniprot