AGTR-2 Antibody

Images

 
Western Blot: AGTR-2 Antibody [NBP1-77368] - Mouse liver tissue lysate with Angiotensin II Type 2 Receptor antibody at 0.5 ug/ml.
Immunocytochemistry/ Immunofluorescence: AGTR-2 Antibody [NBP1-77368] - Immunofluorescence of AGTR-2 in Jurkat cells with AGTR-2 Antibody.
Immunohistochemistry: AGTR-2 Antibody [NBP1-77368] - Representative immunofluorescent immunohistochemical stained images demonstrating the expression of ATIIR2 [red] on GFAP+ CSCs [green]. Negative control was a GBM ...read more
Immunocytochemistry/ Immunofluorescence: AGTR-2 Antibody [NBP1-77368] - Jurkat cell with AGTR2 Antibody at 5 ug/ml.
Immunohistochemistry-Paraffin: AGTR-2 Antibody [NBP1-77368] - Rat liver tissue with AGTR2 antibody at 5 ug/ml.
Immunohistochemistry-Paraffin: AGTR-2 Antibody [NBP1-77368] - Representative 3,3-diaminobenzidine immunohistochemical stained images demonstrating cytoplasmic expression of SOX2, PRR, by cells within GBM, and the ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, ShSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

AGTR-2 Antibody Summary

Immunogen
AGTR2 antibody was raised against a 16 amino acid synthetic peptide from near the center of human AGTR2. The immunogen is located within amino acids 220 - 270 of AGTR2. Amino Acid Squence: LKTNSYGKNRITRDQV
Predicted Species
Sheep (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
AGTR2
Purity
Peptide affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 0.5 ug/ml
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 1-5 ug/ml
  • Immunohistochemistry 5 ug/ml
  • Immunohistochemistry-Paraffin 5 ug/ml
Application Notes
Use in ICC/IF reported in scientific literature (PMID 27200356).
Theoretical MW
36 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control Peptide
AGTR-2 Protein (NBP1-77368PEP)
Publications
Read Publications using
NBP1-77368 in the following applications:

  • 3 publications
  • IHC
    5 publications
  • 7 publications
  • WB
    3 publications

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for AGTR-2 Antibody

  • AGTR2
  • AGTR-2
  • Angiostensin Receptor
  • angiotensin II receptor, type 2
  • Angiotensin II type-2 receptor
  • angiotensin receptor 2
  • AT2
  • AT2ATGR2
  • AT2R
  • MRX88
  • MRX88type-2 angiotensin II receptor

Background

Angiotensin II is a potent vasopressor hormone and a primary regulator of aldosterone secretion that acts through at least two types of receptors, AGTR1 and AGTR2. It is an important effector controlling blood pressure and volume in the cardiovascular system and plays a major role in the development of the mammalian kidney and urinary tract. Like AGTR1, AGTR2 is a seven transmembrane G protein-coupled receptor (GPCR), but AGTR2 does not demonstrate most of the classic features of GPCR signaling. AGTR2 is involved in a wide range of activities, including the induction of neurite outgrowth and the inhibition of cellular proliferation, in addition to the known function of mediation of vasoconstriction.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for AGTR-2 Antibody (NBP1-77368)(17)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 4 applications: ICC/IF, IHC, IHC-P, WB.


Filter By Application
ICC/IF
(3)
IHC
(5)
IHC-P
(7)
WB
(3)
All Applications
Filter By Species
Human
(11)
Mouse
(2)
Rat
(2)
All Species
Showing Publications 1 - 10 of 17. Show All 17 Publications.
Publications using NBP1-77368 Applications Species
Chen H, Zhu Y, Zhao X Prenatal ethanol exposure increased the susceptibility of adult offspring rats to glomerulosclerosis Toxicol. Lett. Dec 4 2019 [PMID: 31811911] (WB, Rat) WB Rat
On N, Koh SP, Brasch HD et al. Embryonic Stem Cell-Like Population in Dupuytren's Disease Expresses Components of the Renin-Angiotensin System Plast Reconstr Surg Glob Open 2017 Jul 01 [PMID: 28831359] (IHC-P, Human) IHC-P Human
Wickremesekera A, Brasch H, Lee V et al. Cancer stem cell subpopulations in metastatic melanoma to the brain express components of the renin-angiotensin system JCMT Aug 27 2019
Tan EMS, Brasch HD, Davis PF et al. Embryonic Stem Cell-like Population within Venous Malformation Expresses the Renin-Angiotensin System Plast Reconstr Surg Glob Open Apr 1 2019 [PMID: 31321175] (IHC-P, ICC/IF, Human) IHC-P, ICC/IF Human
James NE, Cantillo E, Yano N et al. Expression of Components of the Renin-Angiotensin System by the Putative Stem Cell Population Within WHO Grade I Meningioma Front. Surg. May 16 2019 [PMID: 31157231] (IHC-P, Human) IHC-P Human
Papali'i-Curtin, JC;Brasch, HD;van Schaijik, B;de Jongh, J;Marsh, RW;Tan, ST;Itinteang, T; Expression of Components of the Renin-Angiotensin System in Pyogenic Granuloma Front Surg Apr 9 2019 [PMID: 31024924] (IHC-P, Human) IHC-P Human
Nallaiah S, Lee V, Brasch H et al. Cancer Stem Cells within Moderately Differentiated Head and Neck Cutaneous Squamous Cell Carcinoma Express Components of the Renin-angiotensin System. Journal of Plastic, Reconstructive & Aesthetic Surgery. Nov 1 2018 [PMID: 30528285] (IHC-P, Human) IHC-P Human
Spaans F, Quon A, Rowe SR et al. Alterations in vascular function by syncytiotrophoblast extracellular vesicles via LOX-1 in mouse uterine arteries. Clin. Sci. Oct 23 2018 [PMID: 30352791] (ICC/IF, Mouse) ICC/IF Mouse
Ram RS, Brasch HD, Dunne JC et al. Cancer Stem Cells in Moderately Differentiated Lip Squamous Cell Carcinoma Express Components of the Renin-Angiotensin System. Front Surg. 2017 Jun 21 [PMID: 28634582] (IHC, Human) IHC Human
Featherston T, Yu HH, Dunne JC et al. Cancer Stem Cells in Moderately Differentiated Buccal Mucosal Squamous Cell Carcinoma Express Components of the Renin-Angiotensin System. Front Surg. Oct 12 2016 [PMID: 27730124] (IHC, Human) IHC Human
Show All 17 Publications.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for AGTR-2 Antibody (NBP1-77368) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP1-77368AF350
Alexa Fluor 405 NBP1-77368AF405
Alexa Fluor 488 NBP1-77368AF488
Alexa Fluor 532 NBP1-77368AF532
Alexa Fluor 594 NBP1-77368AF594
Alexa Fluor 647 NBP1-77368AF647
Alexa Fluor 700 NBP1-77368AF700
Alexa Fluor 750 NBP1-77368AF750
Biotin NBP1-77368B
DyLight 350 NBP1-77368UV
DyLight 405 NBP1-77368V
DyLight 488 NBP1-77368G
DyLight 550 NBP1-77368R
DyLight 594 NBP1-77368DL594
DyLight 650 NBP1-77368C
DyLight 680 NBP1-77368FR
DyLight 755 NBP1-77368IR
FITC NBP1-77368F
HRP NBP1-77368H
Janelia Fluor 549 NBP1-77368JF549
Janelia Fluor 646 NBP1-77368JF646

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Bioinformatics Tool for AGTR-2 Antibody (NBP1-77368)

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Bioinformatics

Gene Symbol AGTR2
Uniprot