JMY Antibody

Immunohistochemistry: JMY Antibody [NBP1-30464] - Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-JMY used at a dilution of 1:1,000 (1ug/ml). Detection: DAB

Immunohistochemistry-Paraffin: JMY Antibody [NBP1-30464] - FFPE section of human colon carcinoma. Antibody used at a dilution of 1:250 Detection: DAB staining using Immunohistochemistry Accessory Kit.

Immunoprecipitation: JMY Antibody [NBP1-30464] - Whole cell lysate (1 mg for IP, 20% of IP loaded) from HeLa cells. Antibodies: Affinity purified rabbit anti-JMY antibody NBP1-30464 used for IP at 3 mcg/mg lysate. JMY was less efficiently immunoprecipitated by rabbit anti-JMY antibody NBP1-30465, which recognizes a downstream epitope.

• Reactivity: Hu
• Applications: IHC, IHC-P, IP, WB (-)
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 1.0 mg/ml

JMY Antibody Summary

• Immunogen: The immunogen for this product maps to a region between residue 1 and 50 of human junction mediating and regulatory protein using the numbering given in entry NP_689618.3 (GeneID 133746).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: JMY
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunoprecipitation 2-5 ug/mg lysate

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for JMY Antibody

• FLJ37870
• junction mediating and regulatory protein, p53 cofactor
• junction-mediating and regulatory protein
• junction-mediating and -regulatory protein
• MGC163496
• WAS protein homology region 2 domain containing 1-like 3
• WHDC1L3

Background

Cofactor that increases p53/TP53 response via its interaction with p300/EP300. Increases p53/TP53-dependenttranscription and apoptosis, suggesting an important role in p53/TP53 stress response such as DNA damage (Bysimilarity)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: JMY