TTC5 Antibody - BSA Free

Western Blot: TTC5 Antibody [NBP1-76636] - RAW264.7 cell lysate with TTC5 antibody at (A) 0.5, (B) 1 and (C) 2 ug/ml.

Immunohistochemistry-Paraffin: TTC5 Antibody [NBP1-76636] - Mouse brain tissue with TTC5 antibody at 10 ug/ml.

Immunocytochemistry/ Immunofluorescence: TTC5 Antibody - BSA Free [NBP1-76636] - Immunofluorescence of TTC5 in Mouse Brain cells with TTC5 antibody at 20 ug/mL.

• Reactivity: Hu, Mu, Rt, Bv
• Applications: WB, ELISA, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

TTC5 Antibody - BSA Free Summary

• Immunogen: Antibody was raised against a 14 amino acid synthetic peptide from near the carboxy terminus of human TTC5. The immunogen is located within the last 50 amino acids of TTC5. Amino Acid Squence: SSSQASATVASRPQ
• Predicted Species: Rat (100%), Bovine (93%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TTC5
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunocytochemistry/ Immunofluorescence 20 ug/mL
  • Immunohistochemistry 10 ug/ml
  • Immunohistochemistry-Paraffin 10 ug/ml
  • Western Blot 0.5-2 ug/ml
• Control Peptide:

  TTC5 Peptide (NBP1-76636PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Affinity purified

Alternate Names for TTC5 Antibody - BSA Free

• Strap
• tetratricopeptide repeat domain 5
• tetratricopeptide repeat protein 5
• TPR repeat protein 5

Background

Tetratricopeptide repeat protein 5 (TTC5) is a member of a diverse group of functionally distinct proteins that are characterized by containing one or more tetratricopeptide repeats. Each motif consists of two anti-parallel a-helices such that tandem arrays of TPR motifs generate a right-handed helical structure with an amphipathic channel that may serve to accommodate the complementary region of a target protein. While the exact function of TTC5 remains unclear, it is thought that the TPR motifs serve to mediate protein-protein interactions such as those seen with protein chaperones HSP70 and HSP90 and some proteins involved in cell stress response signaling pathways such as protein phosphatase 5, suggesting that TTC5 may also function via protein-protein interactions mediated by its TPR motifs.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TTC5 Antibody (NBP1-76636)(1)

Publication using NBP1-76636

• Batiuk A, Höpfler M, Almeida AC et Al. Soluble ??-tubulins reversibly sequester TTC5 to regulate tubulin mRNA decay Nat Commun 2024-11-17 [PMID: 39551769]

Bioinformatics

• Gene Symbol: TTC5
• Uniprot:
  • Q8N0Z6(Human)