IRP2 Antibody [Biotin]

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Product Details

Summary
Reactivity Mu, Hu, Rt, PmSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Biotin

IRP2 Antibody [Biotin] Summary

Immunogen
A synthetic peptide made to an internal portion of the murine IRP2 protein sequence (between residues 100-200). [UniProt Q811J3]
Localization
Cytoplasmic
Predicted Species
Human (94%), Rat (94%), Primate (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IREB2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
Application Notes
This IRP2 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin-embedded sections and Western blot.
Readout System

Reactivity Notes

Preliminary results have shown poor reactivity against human protein. Immunogen has 94% homology with human, primate and rat proteins.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for IRP2 Antibody [Biotin]

  • ACO3
  • EC 4.2.1.3
  • FLJ23381
  • IRE-BP 2
  • Iron regulatory protein 2
  • iron-responsive element binding protein 2
  • iron-responsive element-binding protein 2
  • IRP2IRP2AD

Background

Iron regulatory protein 2 (IRP2) is a central post-transcriptional regulator of cellular and systemic iron metabolism. It is a cytosolic RNA-binding protein that binds to stem-loop structures. IRP2 is regulated by iron-mediated proteolysis. Hypoxia is important for normal tissue physiology as well as being a component of several pathophysiological conditions, including heart and cerebrovascular diseases and tumor growth. Because iron and oxygen are closely related, IRP2 also plays a role during hypoxia (low oxygen).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for IRP2 Antibody (NB100-1798B) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

DyLight 488 Labeled NB100-1798G
DyLight 550 Labeled NB100-1798R
DyLight 650 Labeled NB100-1798C
HRP Labeled NB100-1798H

Additional IRP2 Products

Bioinformatics Tool for IRP2 Antibody (NB100-1798B)

Discover related pathways, diseases and genes to IRP2 Antibody (NB100-1798B). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for IRP2 Antibody (NB100-1798B)

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Pathways for IRP2 Antibody (NB100-1798B)

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Research Areas for IRP2 Antibody (NB100-1798B)

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Contact Information

Product PDFs

Calculators

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Bioinformatics

Gene Symbol IREB2