Recombinant Mouse IL‑9 (Catalog # 409-ML) stimulates proliferation in the TS1 mouse helper T cell line in a dose-dependent manner (orange line). Proliferation elicited by Recombinant Mouse IL‑9 (0.05 ng/mL) is ...read more
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Protein A or G purified from hybridoma culture supernatant
Reconstitute at 0.5 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for IL-9 Antibody (222622)
IL-9homolog of mouse T cell and mast cell growth factor 40
p40 T-cell and mast cell growth factor
T-cell growth factor P40
IL-9 was originally identified as a T cell-derived T cell growth factor
III/P40 which could support the long term growth of certain mouse T
helper clones in the absence of antigen or antigen-presenting cells.
IL-9 can also prolong the in vitro survival of other T cell
clones as well as potentiate the IL-2 dependent proliferation of mouse
fetal thymocytes. However, this cytokine has no growth-stimulating
activity on mouse cytolytic T cell clones or fresh T cells. Mouse IL-9
also has mast cell enhancing activity (MEA) and can enhance the mIL-3-
or mIL-4-dependent proliferation of mouse bone marrow-derived mast
cells. Furthermore, IL-9 will synergize with erythropoietin to support
erythroid colony formation in vitro. The mouse IL-9 cDNA
encodes a 144 amino acid residue precursor protein with an 18 amino acid
signal peptide that is cleaved to form the mature cysteine-rich protein
with a predicted molecular mass of 14 kDa. Mouse IL-9 contains four
potential N-linked glycosylation sites and the native mIL-9 is a highly
glycosylated protein. Human and mouse IL-9 share 56% amino acid sequence
homology. Although mouse IL-9 is active on human cells, human IL-9 is
not active on mouse cells.
Renauld, J.E. et al. (1995) J. Leukoc. Biol 57:303.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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PRODUCT AVAILABILITY: Update Regarding the Evolving COVID-19 Situation
Bio-Techne appreciates the critical role that you and our products and services play in research efforts to further scientific innovation and discovery. We are continually assessing our manufacturing and supplier capabilities during the COVID-19 situation and are implementing precautionary measures to ensure uninterrupted supply of products and services. Currently, and as we abide by local shelter in place orders across the world, we are fully operational and do not anticipate any material supply disruptions across our Bio-Techne brands and product lines. As the situation evolves, our goal is to utilize preventive measures to reduce the threat that COVID-19 poses to our ability to meet the needs of our customers globally.