IL-31 Antibody

Images

 
Western Blot: IL-31 Antibody [NBP1-77256] - RAW264.7 cell lysate with IL-31 antibody at (A) 2.5, (B) 5 and (C) 10 ug/ml.
Immunohistochemistry-Paraffin: IL-31 Antibody [NBP1-77256] - Rat skeletal muscle tissue with IL-31 antibody at 10 ug/ml.

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, ELISA, IHC, IHC-P, IF
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

IL-31 Antibody Summary

Immunogen
Antibody was raised against a 16 amino acid synthetic peptide from near the amino terminus of mouse IL-31. The immunogen is located within amino acids 30 - 80 of IL-31.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
IL31
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
  • Immunofluorescence
Application Notes
IL-31 antibody can be used for the detection of IL-31 by Western blot at 2. 5 - 5 mg/ml.
Control Peptide
IL-31 Peptide (NBP1-77256PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for IL-31 Antibody

  • IL31
  • IL-31
  • IL-31interleukin-31
  • interleukin 31

Background

Interleukin-31 (IL-31) is a recently discovered T-cell cytokine closely related to IL-6 type cytokines and is preferentially produced by T helper type 2 cells. IL-31 activity is mediated through the ligand-induced oligomerization of a dimeric receptor complex containing IL-31 receptor A and oncostatin M receptor. In response to IL-31 binding, these proteins activate the JAK/STAT and the AKT signaling pathways. RNA levels of IL-31 receptor A and oncostatin M receptor are induced in activated monocytes but are expressed constitutively in epithelial cells. IL-31, when overexpressed in transgenic mice, results in the development of pruritis, alopecia, and skin lesions and in humans may result in atopic dermatitis, suggesting that IL-31 may represent a novel target for antipruritic drug development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

AF2769
Species: Hu
Applications: WB, Flow, CyTOF-ready, ICC
AF662
Species: Mu
Applications: WB, IHC
NB100-68142
Species: Hu
Applications: WB, PEP-ELISA
MAB15041
Species: Hu
Applications: WB, IHC, CyTOF-ready, ICFlow
NBP2-01134
Species: Hu
Applications: WB, IHC, IHC-P
MAB208
Species: Hu
Applications: WB, CyTOF-ready, ELISA(Cap), ELISA(Det), ICC, ICFlow, Neut, ELISA(Sta)
NBP1-32744
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P
NBP2-22471
Species: Hu, Mu, Rt, Mk, Pm
Applications: WB, ChIP, ICC/IF, IHC, IHC-P, IP
NBP1-90058
Species: Hu
Applications: WB, IHC, IHC-P
NBP1-77256
Species: Mu
Applications: WB, ELISA, IHC, IHC-P, IF

Publications for IL-31 Antibody (NBP1-77256) (0)

There are no publications for IL-31 Antibody (NBP1-77256).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for IL-31 Antibody (NBP1-77256) (0)

There are no reviews for IL-31 Antibody (NBP1-77256). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen
  • 1st to review with an image -- $50/€35/£30/$50 CAD/¥300 Yuan/¥5000 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for IL-31 Antibody (NBP1-77256) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Additional IL-31 Products

Bioinformatics Tool for IL-31 Antibody (NBP1-77256)

Discover related pathways, diseases and genes to IL-31 Antibody (NBP1-77256). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for IL-31 Antibody (NBP1-77256)

Discover more about diseases related to IL-31 Antibody (NBP1-77256).
 

Pathways for IL-31 Antibody (NBP1-77256)

View related products by pathway.

PTMs for IL-31 Antibody (NBP1-77256)

Learn more about PTMs related to IL-31 Antibody (NBP1-77256).

Blogs on IL-31

There are no specific blogs for IL-31, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our IL-31 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol IL31
Entrez
Uniprot