IL-18 R beta/IL-1 R7/ACPL Antibody [Unconjugated]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Unconjugated
• Concentration: LYOPH

IL-18 R beta/IL-1 R7/ACPL Antibody [Unconjugated] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse IL‑18 R beta /IL‑1 R7
  Phe20-Glu356
  Accession # Q9Z2B1
• Specificity: Detects mouse IL‑18 R beta /IL‑1 R7 in direct ELISAs and Western blots. In direct ELISAs, less than 5% cross‑reactivity with recombinant mouse IL-18 R is observed.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: IL18RAP
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for IL-18 R beta/IL-1 R7/ACPL Antibody [Unconjugated]

• Accessory protein-like
• AcPL
• CD218 antigen-like family member B
• CD218b antigen
• CD218b
• CDw218b
• IL-1 R7
• IL-18 R beta
• IL-18 receptor accessory protein
• IL-18 receptor beta
• IL18R beta
• IL-18RAcP
• IL18RAP
• IL18RB
• IL-18Rb
• IL-18Rbeta
• IL-18R-beta
• IL-1R accessory protein-like
• IL1R7
• IL-1R7
• IL-1R-7
• IL-1RAcPL
• interleukin 18 receptor accessory protein
• Interleukin-1 receptor 7
• interleukin-18 receptor accessory protein
• Interleukin-18 receptor accessory protein-like
• Interleukin-18 receptor beta
• MGC120589
• MGC120590

Background

IL-18 R beta , also referred to as Accessory Protein-like (AcPL), is a member of the IL-1 receptor superfamily and is designated IL-1 R7.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for IL-18 R beta/IL-1 R7/ACPL Antibody (AF199)(2)

Publications using AF199

• C Eitan, A Siany, E Barkan, T Olender, KR van Eijk, M Moisse, SMK Farhan, YM Danino, E Yanowski, H Marmor-Kol, N Rivkin, NS Yacovzada, ST Hung, J Cooper-Kno, CH Yu, C Louis, SL Masters, KP Kenna, RAA van der Sp, W Sproviero, A Al Khleifa, A Iacoangeli, A Shatunov, AR Jones, Y Elbaz-Alon, Y Cohen, E Chapnik, D Rothschild, O Weissbrod, G Beck, E Ainbinder, S Ben-Dor, S Werneburg, DP Schafer, RH Brown, PJ Shaw, P Van Damme, LH van den Be, H Phatnani, E Segal, JK Ichida, A Al-Chalabi, JH Veldink, Project Mi, NYGC ALS C, E Hornstein Whole-genome sequencing reveals that variants in the Interleukin 18 Receptor Accessory Protein 3'UTR protect against ALS Nature Neuroscience, 2022-03-31;25(4):433-445. 2022-03-31 [PMID: 35361972] (Flow Cytometry, Mouse)
• Chandrasekar B, Patel DN, Mummidi S, Kim JW, Clark RA, Valente AJ Interleukin-18 suppresses adiponectin expression in 3T3-L1 adipocytes via a novel signal transduction pathway involving ERK1/2-dependent NFATc4 phosphorylation. J. Biol. Chem., 2007-12-17;283(7):4200-9. 2007-12-17 [PMID: 18086672] (Flow Cytometry, Mouse)

Bioinformatics

• Gene Symbol: IL18RAP
• Uniprot:
  • Q9Z2B1()