ICAM-3/CD50 Antibody (76205)

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, B/N
Clone
76205
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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Catalog# & Formulation Size Price

ICAM-3/CD50 Antibody (76205) Summary

Immunogen
Mouse myeloma cell line NS0-derived recombinant human ICAM‑3/CD50
Gln30-His485
Accession # CAA49473
Specificity
Detects human ICAM-3/CD50 in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) ICAM‑1 or rhICAM-2.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ICAM3
Purity
Protein A or G purified from ascites
Endotoxin Note
<0.10 EU per 1 μg of the antibody by the LAL method.
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
  • Adhesion Blockade
Publications
Read Publication using
MAB813 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Purity
Protein A or G purified from ascites
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for ICAM-3/CD50 Antibody (76205)

  • CD50 antigen
  • CD50
  • CDW50CDw50
  • ICAM3
  • ICAM-3
  • ICAM-Rintercellular adhesion molecule-3
  • intercellular adhesion molecule 3

Background

Intercellular Adhesion Molecule-3 (ICAM-3; also known as CD50), a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and alpha d/ beta 2. ICAM‑3 is expressed on leukocytes and epidermal Langerhans cells. It may play an important role in T cell stimulation by Langerhans cells. ICAM-3 has not been identified in the mouse.

  1. Hayflick, J. et al. (1998) Immunologic Res. 17:313.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for ICAM-3/CD50 Antibody (MAB813)(1)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 1 application: Neut.


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(1)
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Diseases for ICAM-3/CD50 Antibody (MAB813)

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Bioinformatics

Gene Symbol ICAM3
Uniprot