Species: Hu, Ca, Pm
Applications: WB, ICC/IF, IHC
Host: Mouse monoclonal
Species: Hu
Applications: WB, Flow, CyTOF-ready
Host: Goat Polyclonal
Species: Hu
Applications: Flow, IHC, CyTOF-ready
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Host: Mouse Monoclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: Bioactivity
Species: Hu
Applications: AC
Description
All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA1 protein. ICAM3 is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signaling molecule. Upon stimulation by a physiological stimulus it becomes rapidly and transiently phosphorylated on serine residues. N-glycosylated; glycans consist of a mixture of tri and tetra-antennary complex-type chains and high-mannose chains.
Bioinformatics
| Entrez |
Human
|
| Product By Gene ID |
3385 |
| Alternate Names |
- CD50 antigen
- CD50
- CDW50CDw50
- ICAM3
- ICAM-3
- ICAM-Rintercellular adhesion molecule-3
- intercellular adhesion molecule 3
|
Research Areas for ICAM-3/CD50
Find related products by research area and learn more about each of the different research areas below.
Cellular MarkersImmunology
![Flow Cytometry ICAM-3/CD50 Antibody (76203) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab8131_human-icam-3-cd50-mab-clone-76203-flow-cytometry-610202011048.jpg)
![Sandwich ELISA ICAM-3/CD50 Antibody Pair [HRP]](http://images.novusbio.com/fullsize/ICAM-3-CD50-Antibody-Pair-[HRP]-Sandwich-ELISA-NBP2-79571-img0001.jpg)
![N/A ICAM-3/CD50 [Biotin]](http://images.novusbio.com/fullsize2/DATA_ICAM3_DY715_ELISA_2191.jpg)
![Immunohistochemistry ICAM-3/CD50 Antibody (76203) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/mab8131_human-icam-3-cd50-mab-clone-76203-immunohistochemistry-2010202073831.jpg)
