Species: Hu, Ca, Mk
Applications: WB, IHC, IF
Host: Mouse monoclonal
WB, Flow, IP, ELISA(Cap), ICCHost:
WB, Flow, AdBlk, CyTOF-readyHost:
Applications: WB, ELISA, PA
Applications: RNAi, RNAi SP
All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signalling molecule. ICAM 3 is the major ligand for LFA-1 in the resting state.
Research Areas for ICAM-3/CD50
Find related products by research area and learn more about each of the different research areas below.Cellular MarkersImmunology
Bioinformatics Tool for ICAM-3/CD50
Discover related pathways, diseases and genes to ICAM-3/CD50. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.