ICAM-3/CD50 Antibody (76205) [Alexa Fluor® 750]

• Applications: WB, B/N
• Clone: 76205
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 750

ICAM-3/CD50 Antibody (76205) [Alexa Fluor® 750] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human ICAM‑3/CD50
  Gln30-His485
  Accession # CAA49473
• Specificity: Detects human ICAM-3/CD50 in direct ELISAs and Western blots. Does not cross-react with recombinant human (rh) ICAM‑1 or rhICAM-2.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Intercellular Adhesion Molecule-3 (ICAM-3; also known as CD50), a member of the immunoglobulin superfamily, binds the leukocyte integrins LFA-1 (CD11a/CD18) and alpha _d/ beta ₂. ICAM‑3 is expressed on leukocytes and epidermal Langerhans cells. It may play an important role in T cell stimulation by Langerhans cells. ICAM-3 has not been identified in the mouse.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.