Home » HO-1/HMOX1/HSP32 » HO-1/HMOX1/HSP32 Antibodies » HO-1/HMOX1/HSP32 Antibody (1F12.A6)

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HO-1/HMOX1/HSP32 Antibody (1F12.A6)

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Product Details

Summary
Product Discontinued
View other related HO-1/HMOX1/HSP32 Primary Antibodies

Order Details


    • Catalog Number
      NBP1-18944
    • Availability
      Product Discontinued

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HO-1/HMOX1/HSP32 Antibody (1F12.A6) Summary

Immunogen
Synthetic peptide corresponding to aa 1-30 of human heme-oxygenase 1.
Marker
Oxidative Stress Marker
Specificity
This recognizes human, mouse, and bovine HO-1. Other species have not been tested. It does not cross-react with HO-2.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
HMOX1
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.
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Applications/Dilutions

Dilutions
  • ELISA 1 ug/ml
  • Western Blot 0.5-1 ug/ml
Application Notes
ELISA and Immunoblotting In IB a band of approx. 32 kDa is detected.

Reactivity Notes

Please note that this antibody is reactive to Mouse and derived from the same host, Mouse. Additional Mouse on Mouse blocking steps may be required for IHC and ICC experiments. Please contact Technical Support for more information.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.4)
Preservative
No Preservative
Purity
Protein G purified

Alternate Names for HO-1/HMOX1/HSP32 Antibody (1F12.A6)

  • bK286B10
  • EC 1.14.99.3
  • heat shock protein, 32-kD
  • heme oxygenase (decycling) 1
  • HMOX1
  • HO
  • HO1
  • HO-1
  • HO-1heme oxygenase 1
  • HSP32

Background

Heme-oxygenase is an enzyme that catalyzes heme catabolism to yield biliverdin, iron, and carbon monoxide (CO). There are three isoforms of heme-oxygenase: HO-1, HO-2, and HO-3. HO-1 and HO-2 have been identified as the two major isoforms in mammals. HO-1, also known as heat shock protein 32 (Hsp32) is induced by most oxidative stress inducers, cytokines, inflammatory agents, and heat shock. HO-1 deficiency appears to cause reduced stress defense, a pro-inflammatory tendency, susceptibility to atherosclerotic lesion formation, endothelial cell injury, and growth retardation. Therefore, up-regulation of HO-1 is one of the major defense mechanisms against oxidative stress.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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HO-1/HMOX1/HSP32
Antibody (1F12.A6)
NBP1-18944
HO-1/HMOX1/HSP32 Antibody (1F12.A6)
Species: Hu, Mu, Bv
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Bioinformatics

Gene Symbol HMOX1
Entrez