gtf3c3 Antibody - BSA Free

Immunoprecipitation: gtf3c3 Antibody [NB100-60430] - Detection of Human GTF3C3/TFIIIC102 on HeLa whole cell lysate using NB100-60430. GTF3C3/TFIIIC102 was also immunoprecipitated by rabbit anti-GTF3C3/TFIIIC102 antibody NB100-60431.

• Reactivity: Hu
• Applications: IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

gtf3c3 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit gtf3c3 Antibody - BSA Free (NB100-60430) is a polyclonal antibody validated for use in IP. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: The immunogen recognized by this antibody maps to a region between residue 100 and 150 of human general transcription factor 3C polypeptide 3 (Transcription factor IIIC 102 kDa subunit) using the numbering given in entry NP_036218.1 (GeneID 9330).
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GTF3C3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoprecipitation 1:10-1:500
• Application Notes: This antibody is not recommended for Western Blot analysis.

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for gtf3c3 Antibody - BSA Free

• general transcription factor 3C polypeptide 3
• general transcription factor IIIC, polypeptide 3, 102kDa
• TF3C-gamma
• TFIIIC 102 kDa subunit
• TFIIIC102general transcription factor IIIC, polypeptide 3 (102kD)
• TFiiiC2-102
• TFIIICgamma
• Transcription factor IIIC 102 kDa subunit
• Transcription factor IIIC subunit gamma
• transcription factor IIIC, 102 kD

Background

General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity. Alternate names for GTF3C3/TFIIIC102 include general transcription factor 3C polypeptide 3, transcription factor IIIC subunit gamma, TF3C-gamma, TFIIIC 102 kDa subunit, TFIIIC102, and general transcription factor IIIC polypeptide 3 (beta subunit, 102 kDa).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GTF3C3
• Entrez:
  • 9330(Human)
• Uniprot:
  • NP_036218.1(Human)