gtf3c3 Products

Description

General transcription factor 3C polypeptide 3 (GTF3C3/TFIIIC102) is a subunit of the TFIIIC DNA-binding factor required for transcription of tRNA and 5S rRNA genes by RNA polymerase III. Human TFIIIC is composed of six subunits: TFIIIC220, TFIIIC110, TFIIIC102, TFIIIC90 and TFIIIC63, and TFIIIC35. GTF3C3/TFIIIC102 appears to be important for stable complex formation and recruitment of RNA polymerase III by interacting with TFIIIB90, TBP, and TFIIIC63. GTF3C3/TFIIIC102 has been shown to also interact with DEDD and FLAME-3 proteins. This interaction may function to translocate GTF3C3/TFIIIC102 to the nucleus and regulate TFIIIC activity.

Bioinformatics

Entrez	9330 Human 98488 Mouse
Uniprot	NP_036218 Human NP_036218.1 Human Q9Y5Q9 Human
Product By Gene ID	9330
Alternate Names	general transcription factor 3C polypeptide 3 general transcription factor IIIC, polypeptide 3, 102kDa TF3C-gamma TFIIIC 102 kDa subunit TFIIIC102general transcription factor IIIC, polypeptide 3 (102kD) TFiiiC2-102 TFIIICgamma Transcription factor IIIC 102 kDa subunit Transcription factor IIIC subunit gamma transcription factor IIIC, 102 kD