Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody (007) - Azide and BSA Free

Western Blot: Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody (007) [NBP2-89413] - Lane A: PC3 Whole Cell Lysate Lysates/proteins at 30 ug per lane.Secondary Goat Anti-Rabbit IgG H&L (Dylight800) at 1/10000 dilution.Developed using the Odyssey technique. Performed under reducing conditions.Predicted band size:62 kDa Observed band size:95 kDa

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 007
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody (007) - Azide and BSA Free Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human Glucosamine (N-acetyl)-6-Sulfatase/GNS (Accession#: NP_002067.1; Met 1-Leu 552).
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: GNS
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:5000-1:10000
  • Western Blot 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody (007) - Azide and BSA Free

• EC 3.1.6
• EC 3.1.6.14
• G6Sglucosamine-6-sulfatase
• glucosamine (N-acetyl)-6-sulfatase
• Glucosamine6Sulfatase
• Glucosamine-6-Sulfatase
• GNS
• MGC21274
• N-acetylglucosamine-6-sulfatase

Background

The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody (NBP2-89413)(1)

Publication using NBP2-89413

• Jo HH, Goh YS, Kim HJ et al. Tacrolimus Improves Therapeutic Efficacy of Umbilical Cord Blood-Derived Mesenchymal Stem Cells in Diabetic Retinopathy by Suppressing DRP1-Mediated Mitochondrial Fission Antioxidants (Basel, Switzerland) 2023-09-06 [PMID: 37760030] (WB, Rat)

Bioinformatics

• Gene Symbol: GNS