Arylsulfatase B/ARSB Antibody (708401)

Images

 
Western blot shows lysates of HepG2 human hepatocellular carcinoma cell line, Huh‑7 human hepatoma cell line, and human skeletal muscle tissue. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human ...read more
Arylsulfatase B/ARSB was detected in immersion fixed HepG2 human hepatocellular carcinoma cell line using Mouse Anti-Human Arylsulfatase B/ARSB Monoclonal Antibody (Catalog # MAB4415) at 10 µg/mL for 3 hours at room ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ICC/IF
Clone
708401
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

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Catalog# & Formulation Size Price

Arylsulfatase B/ARSB Antibody (708401) Summary

Immunogen
Chinese hamster ovary cell line CHO-derived recombinant human Arylsulfatase B/ARSB
Ser37-Met533
Accession # P15848
Specificity
Detects human Arylsulfatase B/ARSB in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant human (rh) ARSA, rhARSJ, or recombinant mouse ARSG is observed.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
ARSB
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
  • Immunocytochemistry 8-25 ug/mL
Reviewed Applications
Read 1 Review rated 5
using
MAB4415 in the following applications:

Publications
Read Publications using
MAB4415 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Sterile PBS to a final concentration of 0.5 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Arylsulfatase B/ARSB Antibody (708401)

  • ARSB
  • Arylsulfatase B
  • ASB
  • EC 3.1.6.12
  • G4S
  • MPS6
  • N-acetylgalactosamine-4-sulfatase

Background

Arylsulfatase B (ARSB) is a lysosomal enzyme of the sulfatase family that functions as an N-acetylgalactosamine-4-sulfatase (1). The enzyme is also active against chondroitin sulfate and dermatan sulfate (2). Deficiencies in ARSB activity are responsible for the lysosomal storage disease mucopolysaccharidosis Type VI, also known as Maroteaux-Lamy Syndrome (3).

  1. Peters, C. et al. (1990) J. Biol. Chem. 265:3374.
  2. O’Brien, J.S. et al. (1974) Biochem. Biophys. Res. Commun. 60:1170.
  3. Wicker, G. et al. (1991) J. Biol. Chem. 266:21386.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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MAB4415
Species: Hu
Applications: WB, ICC/IF

Publications for Arylsulfatase B/ARSB Antibody (MAB4415)(2)

Review for Arylsulfatase B/ARSB Antibody (MAB4415) (1) 51

Average Rating: 5
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using MAB4415:
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WB
(1)
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(1)
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Images Ratings Applications Species Date Details
 
reviewed by:
Anonymous
WB Human 02/20/2015
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Summary

ApplicationWestern Blot
Sample TestedSee PMID 22902879
SpeciesHuman

Blocking

Blocking DetailsSee PMID 22902879

Details

Detection NotesSee PMID 22902879

Comments

CommentsIndependent review from antibodyresource.com

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Recent Reviews

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1
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Anonymous
02/20/2015
Application: WB
Species: Human

Bioinformatics

Gene Symbol ARSB
Uniprot
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