Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody (007) [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 007
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 594

Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody (007) [Alexa Fluor™ Plus 594] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human Glucosamine (N-acetyl)-6-Sulfatase/GNS (Accession#: NP_002067.1; Met 1-Leu 552).
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: GNS
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Glucosamine (N-acetyl)-6-Sulfatase/GNS Antibody (007) [Alexa Fluor™ Plus 594]

• EC 3.1.6
• EC 3.1.6.14
• G6Sglucosamine-6-sulfatase
• glucosamine (N-acetyl)-6-sulfatase
• Glucosamine6Sulfatase
• Glucosamine-6-Sulfatase
• GNS
• MGC21274
• N-acetylglucosamine-6-sulfatase

Background

The product of this gene is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GNS