KIR2.3 Antibody

Images

 
Western Blot: KIR2.3 Antibody [NBP3-03005] - Analysis of extracts of various cell lines, using KIR2.3 antibody at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. ...read more
Immunohistochemistry-Paraffin: KIR2.3 Antibody [NBP3-03005] - Paraffin-embedded rat brain using KIR2.3 antibody at dilution of 1:100 (40x lens).

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

KIR2.3 Antibody Summary

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KIR2.3 (NP_004972.1).
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
KCNJ4
Purity
Affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 1:50-1:200
  • Immunohistochemistry-Paraffin
  • Western Blot 1:500-1:2000
Theoretical MW
49 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS with 50% glycerol, pH7.3.
Preservative
0.02% Sodium Azide
Purity
Affinity purified

Alternate Names for KIR2.3 Antibody

  • hippocampal inward rectifier potassium channel
  • Hippocampal inward rectifier
  • HIR
  • HIRhIRK2
  • HIRK2
  • HRK1
  • HRK1MGC142066
  • Inward rectifier K(+) channel Kir2.3
  • inward rectifier K+ channel Kir2.3
  • inward rectifier potassium channel 4
  • IRK3
  • IRK-3
  • IRK3MGC142068
  • KCNJ4
  • KIR2.3
  • Potassium channel, inwardly rectifying subfamily J member 4
  • potassium inwardly-rectifying channel, subfamily J, member 4

Background

The KIR2.3 (KCNJ4) gene codes for protein that is 445 amino acid long inward rectifier potassium channel that regulates channel flow critical for electrical signaling of the nervous system, allowing for muscle excitability and neural firing. The KCNJ4 has a mass of approximately 49 kDA. Researchers are investigating the role of the KIR2.3 gene in meniere's disease, neuronitis, hyperglycemia, and noma. This gene has been shown to interact with other genes such as LIN7B, CASK, DLG4, IL16, and DLG1 in pathways such as potassium transport (in and out), antiarrhythmic pathways, dopamine-DARPP32 feedback onto cAMP pathways, and in the cholinergic synapse.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol KCNJ4