GDF-11/BMP-11 Antibody [PerCP]

• Reactivity: Hu, Mu
• Applications: IHC
• Clonality: Polyclonal
• Host: Goat
• Conjugate: PerCP

GDF-11/BMP-11 Antibody [PerCP] Summary

• Immunogen: E. coli-derived recombinant human GDF‑11/BMP‑11
  Asn299-Ser407
  Accession # O95390
• Specificity: Detects human and mouse GDF‑11/BMP‑11 in direct ELISAs and Western blots. In direct ELISAs, no cross-reactivity with recombinant human/mouse/rat GDF-8/Myostatin and less than 1% cross-reactivity with recombinant human BMP-6 is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: GDF11
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: PBS
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for GDF-11/BMP-11 Antibody [PerCP]

• BMP11
• BMP-11
• BMP-11BMP11Bone morphogenetic protein 11
• GDF11
• GDF-11
• growth differentiation factor 11
• growth/differentiation factor 11

Background

BMP11 is encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GDF11