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CTS002) and counterstained with hematoxylin (blue). Lower panel shows a lack of labeling when primary antibodies are omitted and tissue is stained only with secondary antibody followed by incubation with detection reagents. Specific staining was localized to epithelia of the colon. View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections." class="big_lightbox" target="_blank">
1958-GD induces hemoglobin expression in the K562 human chronic myelogenous leukemia cell line. The ED50 for this effect is 0.8‑4.8 ng/mL." class="big_lightbox" target="_blank">
1958-GD protein was resolved with SDS-PAGE under reducing (R) and non-reducing (NR) conditions and visualized by silver staining, showing bands at 13 kDa and 21 kDa, respectively." class="big_lightbox" target="_blank">
1958-GD. The peak at 25163 Da corresponds to the calculated molecular mass of the disulfide-linked homodimer." class="big_lightbox" target="_blank">
BMP11 is encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.
![Immunohistochemistry GDF-11/BMP-11 Antibody [Unconjugated]](http://images.novusbio.com/images/antibody/GDF11_AF1958_Immunohistochemistry_16463.jpg)
![N/A GDF-11/BMP-11 [Biotin]](http://images.novusbio.com/fullsize/elisa/DATA_GDF11_DY195805_ELISA_2382.jpg)
![Bioactivity GDF-11/BMP-11 [Unconjugated]](http://images.novusbio.com/images/protein/GDF-11_1958-GD_700.jpg)
![SDS-Page GDF-11/BMP-11 [Unconjugated]](http://images.novusbio.com/images/protein/GDF-11_1958-GD_698.jpg)
![Mass Spectrometry GDF-11/BMP-11 [Unconjugated]](http://images.novusbio.com/images/protein/GDF-11_1958-GD_829.jpg)
