Western blot shows lysates of HeLa human cervical epithelial carcinoma cell line, HepG2 human hepatocellular carcinoma cell line, and Raji human Burkitt's lymphoma cell line. PVDF membrane was probed with 0.2 µg/mL of ...read more
TGF-beta RI/ALK‑5 was detected in immersion fixed human peripheral blood mononuclear cells (PBMCs) stimulated with LPS and monensin using Goat Anti-Human TGF‑ beta RI/ALK‑5 Antigen Affinity-purified Polyclonal ...read more
Mouse myeloma cell line NS0-derived recombinant human TGF-beta RI/ALK-5 Leu34-Glu125 Accession # P36897
Detects human TGF-beta RI/ALK-5 in direct ELISAs and Western blots. In direct ELISAs, approximately 50% cross-reactivity with recombinant mouse TGF‑ beta RI is observed and less than 5% cross-reactivity with recombinant human (rh) TGF-beta RII and rhTGF-beta RIII is observed.
Test in a species/application not listed above to receive a full credit towards a future purchase.
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitute at 0.2 mg/mL in sterile PBS.
This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.
Alternate Names for TGF-beta RI/ALK-5 Antibody [Unconjugated]
activin A receptor type II-like kinase, 53kD
activin A receptor type II-like kinase, 53kDa
Activin receptor-like kinase 5
Serine/threonine-protein kinase receptor R4
TGF-beta receptor type I
TGF-beta receptor type-1
TGF-beta type I receptor
transforming growth factor beta receptor I
transforming growth factor, beta receptor 1
transforming growth factor, beta receptor I (activin A receptor type II-likekinase, 53kD)
Transforming growth factor-beta receptor type I
TGF-beta RI, also known as activin-like kinase 5 (ALK-5), is a 55 kDa type I transmembrane serine/threonine receptor kinase. It is ubiquitously expressed and forms a functional heterotetrameric signaling TGF-beta receptor complex with TGF-beta RII. The amino acid sequence of human TGF-beta RI extracellular domain is 91%, 90%, 91%, and 93% identical to that of porcine, mouse, bovine, and rat TGF-beta RI, respectively.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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