GDF-11/BMP-11 Antibody (3G6) - Azide and BSA Free

Immunohistochemistry-Paraffin: GDF-11/BMP-11 Antibody (3G6) [H00010220-M01] - Analysis of monoclonal antibody to GDF11 on formalin-fixed paraffin-embedded human pancreas. Antibody concentration 3 ug/ml.

• Reactivity: Hu
• Applications: ELISA, IHC
• Clone: 3G6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

GDF-11/BMP-11 Antibody (3G6) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse GDF-11/BMP-11 Antibody (3G6) - Azide and BSA Free (H00010220-M01) is a monoclonal antibody validated for use in IHC and ELISA. Anti-GDF-11/BMP-11 Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: GDF11 (NP_005802, 310 a.a. ~ 407 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
• Specificity: GDF11 - growth differentiation factor 11
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: GDF11
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
• Application Notes: Antibody reactive against recombinant protein on ELISA. It has also been used for immunohistochemistry on paraffin sections. Antigen retrieval using 1X citrate buffer (pH 6.0) in pressure cooker under 125? for 4min and under 90? for 45min is recommended.

Reactivity Notes

Other species not tested.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GDF-11/BMP-11 Antibody (3G6) - Azide and BSA Free

• BMP11
• BMP-11
• BMP-11BMP11Bone morphogenetic protein 11
• GDF11
• GDF-11
• growth differentiation factor 11
• growth/differentiation factor 11

Background

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GDF-11/BMP-11 Antibody (H00010220-M01)(1)

Publication using H00010220-M01

• Jackson WM, Aragon AB, Onodera J et al. Cytokine expression in muscle following traumatic injury. J Orthop Res 2011-10-01 [PMID: 21452302] (IHC-P, Human)

Bioinformatics

• Gene Symbol: GDF11
• Entrez:
  • 10220(Human)
• OMIM:
  • 603936(Human)
• Uniprot:
  • NP_005802(Human)