GDF-11/BMP-11 Antibody (1E6) - Azide and BSA Free

Western Blot: GDF-11/BMP-11 Antibody (1E6) [H00010220-M03] - Analysis of GDF11 expression in Jurkat (Cat # L017V1).

Western Blot: GDF-11/BMP-11 Antibody (1E6) [H00010220-M03] - Analysis of GDF11 expression in K-562 (Cat # L009V1).

ELISA: GDF-11/BMP-11 Antibody (1E6) [H00010220-M03] - Detection limit for recombinant GST tagged GDF11 is approximately 0.3ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: WB, ELISA
• Clone: 1E6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

GDF-11/BMP-11 Antibody (1E6) - Azide and BSA Free Summary

• Immunogen: GDF11 (NP_005802, 310 a.a. ~ 407 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ESRCCRYPLTVDFEAFGWDWIIAPKRYKANYCSGQCEYMFMQKYPHTHLVQQANPRGSAGPCCTPTKMSPINMLYFNDKQQIIYGKIPGMVVDRCGCS
• Specificity: GDF11 (1E6)
• Isotype: IgG2a Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: GDF11
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:100-1:2000
  • Western Blot 1:500
• Application Notes: Antibody reactive against cell lysate for western blot. It has also been used for ELISA.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for GDF-11/BMP-11 Antibody (1E6) - Azide and BSA Free

• BMP11
• BMP-11
• BMP-11BMP11Bone morphogenetic protein 11
• GDF11
• GDF-11
• growth differentiation factor 11
• growth/differentiation factor 11

Background

The protein encoded by this gene is a member of the bone morphogenetic protein (BMP) family and the TGF-beta superfamily. This group of proteins is characterized by a polybasic proteolytic processing site which is cleaved to produce a mature protein containing seven conserved cysteine residues. The members of this family are regulators of cell growth and differentiation in both embryonic and adult tissues. Studies in mice and Xenopus suggest that this protein is involved in mesodermal formation and neurogenesis during embryonic development.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for GDF-11/BMP-11 Antibody (H00010220-M03)(1)

Publication using H00010220-M03

• Bajikar SS, Wang CC, Borten MA et al. Tumor-Suppressor Inactivation of GDF11 Occurs by Precursor Sequestration in Triple-Negative Breast Cancer Dev. Cell. 2017-11-20 [PMID: 29161592] (Human)

Bioinformatics

• Gene Symbol: GDF11
• Entrez:
  • 10220(Human)
• OMIM:
  • 603936(Human)
• Uniprot:
  • NP_005802(Human)