G2A/GPR132 Antibody

Images

 
Immunohistochemistry-Paraffin: G2A/GPR132 Antibody [NLS3702] - Analysis of anti-GPR132 / G2A antibody with human spleena at 3 ug/ml.
Immunohistochemistry: G2A/GPR132 Antibody [NLS3702] - IHC of formalin fixed paraffin embedded human spleen at 3 ug/ml.

Product Details

Summary
Reactivity Hu, MkSpecies Glossary
Applications IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml

Order Details

G2A/GPR132 Antibody Summary

Immunogen
Synthetic 18 amino acid peptide from 3rd extracellular domain of human GPR132 / G2A.
Localization
Cell Membrane
Specificity
Human GPR132 / G2A. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except PRDM4 (61%).
Predicted Species
Monkey (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPR132
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:10-1:500

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (100%), Gorilla (100%), Marmost (83%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for G2A/GPR132 Antibody

  • G protein-coupled receptor 132
  • G2 accumulation protein
  • G2A
  • G2AG protein-coupled receptor G2A
  • GPR132
  • MGC99642
  • probable G-protein coupled receptor 132

Background

G2A belongs to the Lysophospholipid/Lysosphingolipid Receptor family and is an anti-proliferative cell cycle regulator that plays a critical role in controlling peripheral lymphocyte homeostasis. Loss of G2A expression leads to the development of a late-onset autoimmune syndrome (Le et al, 2001). Lysophosphatidylcholine (LPC) is the activating ligand for G2A. G2A is expressed in lymphoid tissues. ESTs have been isolated from normal human primary B-cell from tonsil, leukocyte, colon, lung, and pancreas/spleen, melanocyte/uterus/fetal heart libraries and from a human bone marrow cancer library.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

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Bioinformatics

Gene Symbol GPR132
Entrez
Uniprot