OGR1 Antibody - BSA Free

Images

 
Immunohistochemistry-Paraffin: OGR1 Antibody [NLS1194] - Colon, Adenocarcinoma
Immunohistochemistry-Paraffin: OGR1 Antibody [NLS1194] - Analysis of brain, neurons and glia using this antibody at 2 ug/ ml.
Immunohistochemistry-Paraffin: OGR1 Antibody [NLS1194] - Analysis of human kidney.
Immunohistochemistry-Paraffin: OGR1 Antibody [NLS1194] - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Eq, Ha, Pm, Pm, RbSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.0 mg/ml

Order Details

OGR1 Antibody - BSA Free Summary

Immunogen
Synthetic 16 aa peptide from C-Terminus of human OGR1.
Epitope
C-Terminus
Localization
Cell membrane; Multipass membrane protein.
Specificity
Human OGR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GPR68
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 - 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Dog, Bat, Panda, Platypus (88%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for OGR1 Antibody - BSA Free

  • G protein-coupled receptor 68
  • GPR12A
  • GPR68
  • G-protein coupled receptor 68
  • OGR1
  • OGR-1
  • ovarian cancer G protein-coupled receptor, 1
  • ovarian cancer G-protein coupled receptor 1
  • Sphingosylphosphorylcholine receptor

Background

OGR1, a Lysophospholipid/Lysosphingolipid Receptor, was isolated by degenerate PCR from an ovarian cell line cDNA library. It is not expressed in normal ovary. OGR1 binds sphingosylphosporylcholine, a lipid molecule involved in cell growth and survival. Recently, OGR1 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003). OGR1 has been reported to be expressed in blood, brain, heart, kidney, lung, placenta, small intestine, spleen, and testis. ESTs have been isolated from blood, lung, and uterine libraries. Caution: OGR1 is also known as GPR12A, which is distinct from GPR12 in cluster 3851.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GPR68
Entrez