OGR1 Antibody - BSA Free

Immunohistochemistry-Paraffin: OGR1 Antibody [NLS1194] - Colon, Adenocarcinoma

Immunohistochemistry-Paraffin: OGR1 Antibody [NLS1194] - Analysis of brain, neurons and glia using this antibody at 2 ug/ ml.

Immunohistochemistry-Paraffin: OGR1 Antibody [NLS1194] - Analysis of human kidney.

Immunohistochemistry-Paraffin: OGR1 Antibody [NLS1194] - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

• Reactivity: Hu, Mu, Rt, Po, Bv, Eq, Ha, Pm, Pm, Rb
• Applications: IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1.0 mg/ml

OGR1 Antibody - BSA Free Summary

• Immunogen: Synthetic 16 aa peptide from C-Terminus of human OGR1.
• Epitope: C-Terminus
• Localization: Cell membrane; Multipass membrane protein.
• Specificity: Human OGR1. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPR68
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 10 - 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Dog, Bat, Panda, Platypus (88%).

Packaging, Storage & Formulations

• Storage: Keep as concentrated solution. Aliquot and store at -20C or below. Avoid multiple freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Notes

Product can be stored undiluted at 4C for up to 1 month.

Alternate Names for OGR1 Antibody - BSA Free

• G protein-coupled receptor 68
• GPR12A
• GPR68
• G-protein coupled receptor 68
• OGR1
• OGR-1
• ovarian cancer G protein-coupled receptor, 1
• ovarian cancer G-protein coupled receptor 1
• Sphingosylphosphorylcholine receptor

Background

OGR1, a Lysophospholipid/Lysosphingolipid Receptor, was isolated by degenerate PCR from an ovarian cell line cDNA library. It is not expressed in normal ovary. OGR1 binds sphingosylphosporylcholine, a lipid molecule involved in cell growth and survival. Recently, OGR1 has been shown to act as a proton-sensing receptor stimulating inositol phosphate formation (Ludwig et al. 2003). OGR1 has been reported to be expressed in blood, brain, heart, kidney, lung, placenta, small intestine, spleen, and testis. ESTs have been isolated from blood, lung, and uterine libraries. Caution: OGR1 is also known as GPR12A, which is distinct from GPR12 in cluster 3851.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPR68
• Entrez:
  • 8111(Human)