Proprotein Convertase 7/PCSK7 Antibody - BSA Free

Immunohistochemistry: Proprotein Convertase 7/PCSK7 Antibody - BSA Free [NBP3-47196] - Immunohistochemistry of paraffin-embedded human colon cancer using (Proprotein Convertase 7/PCSK7 antibody) at dilution of 1:50

Western Blot: Proprotein Convertase 7/PCSK7 Antibody - BSA Free [NBP3-47196] - Mouse spleen tissue were subjected to SDS PAGE followed by western blot with (Proprotein Convertase 7/PCSK7 Antibody) at dilution of 1:300

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

Proprotein Convertase 7/PCSK7 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit Proprotein Convertase 7/PCSK7 Antibody - BSA Free (NBP3-47196) is a polyclonal antibody validated for use in IHC, WB and ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: proprotein convertase subtilisin/kexin type 7. (Uniprot# Q16549)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PCSK7
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunohistochemistry 1:20-1:200
  • Western Blot 1:500-1:2000
• Theoretical MW: 68 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS, 50% Glycerol, pH (7.3)
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for Proprotein Convertase 7/PCSK7 Antibody - BSA Free

• EC 3.4.21
• EC 3.4.21.-
• EC 3.4.21.61
• EC 3.4.21.75
• EC 3.4.21.93
• hPC8
• LPC
• LPCFLJ23503
• Lymphoma proprotein convertase
• PC7FLJ45329
• PC8prohormone convertase PC7
• PCSK7
• Prohormone convertase 7
• Proprotein Convertase 7
• Proprotein convertase 8
• proprotein convertase subtilisin/kexin type 7
• SPC7
• SPC7proprotein convertase PC7
• Subtilisin/kexin-like protease PC7

Background

PCSK7 is encoded by this gene belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein is a calcium-dependent serine endoprotease. It is structurally related to its family members, PACE and PACE4. This protein is concentrated in the trans-Golgi network, associated with the membranes, and is not secreted. It can process proalbumin and is thought to be responsible for the activation of HIV envelope glycoproteins gp160 and gp140. This gene has been implicated in the transcriptional regulation of housekeeping genes. Multiple alternatively spliced transcripts are described for this gene but their full length nature is not yet known. Downstream of this gene's map location at 11q23-q24, nucleotides that match part of this gene's 3' end are duplicated and inverted. A translocation breakpoint associated with lymphoma occurs between this gene and its inverted counterpart. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PCSK7