Western Blot: Filamin A Antibody [NB100-58812] - Whole cell lysate (5, 15 and 50 ug for WB) from HeLa cells. Antibody used for WB at 0.04 ug/ml.
Immunohistochemistry: Filamin A Antibody [NB100-58812] - Sample: FFPE section of human colon carcinoma. Antibody: Affinity purified rabbit anti-Filamin A used at a dilution of 1:1,000 (0.2ug/ml). Detection: DAB
Actin-binding protein, or filamin, is a 280-kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.[supplied by OMIM]
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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