FIH-1/HIF-1AN Antibody Blocking Peptide

• Reactivity: Hu
• Applications: AC
• Concentration: 1.0 mg/ml

FIH-1/HIF-1AN Antibody Blocking Peptide Summary

• Description: A HIF1AN antibody blocking peptide.
• Specificity: This peptide is specific for NB100-428 only.
• Protein/Peptide Type: Antibody Blocking Peptide
• Gene: HIF1AN

Applications/Dilutions

• Dilutions:
  • Antibody Competition
• Application Notes: This peptide is useful as a blocking peptide for NB 100-428.
  
  For further blocking peptide related protocol, click here.

Packaging, Storage & Formulations

• Storage: Store at -80C. Avoid freeze-thaw cycles.
• Buffer: Peptide dissolved in dH2O. Contains no BSA.
• Preservative: No Preservative
• Concentration: 1.0 mg/ml

Alternate Names for FIH-1/HIF-1AN Antibody Blocking Peptide

• DKFZp762F1811
• EC 1.14.11.16
• factor inhibiting HIF1
• Factor inhibiting HIF-1
• FIH1
• FIH-1
• FIH1FIH-1
• FLJ20615
• FLJ22027
• HIF1AN
• HIF-1AN
• hypoxia inducible factor 1, alpha subunit inhibitor
• hypoxia-inducible factor 1-alpha inhibitor
• Hypoxia-inducible factor asparagine hydroxylase
• Peptide-aspartate beta-dioxygenase

Background

Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: HIF1AN