FIH-1/HIF-1AN Products

Antibodies
Lysates
FIH-1/HIF-1AN Overexpression ...
FIH-1/HIF-1AN Overexpression Lysat...
H00055662-T01
Species: Hu
Applications: WB
FIH-1/HIF-1AN Overexpression ...
FIH-1/HIF-1AN Overexpression Lysat...
NBL1-11541
Applications: WB
Proteins
FIH-1/HIF-1AN Peptide
FIH-1/HIF-1AN Peptide
NB100-428PEP
Species: Hu
FIH-1/HIF-1AN Recombinant Pro ...
FIH-1/HIF-1AN Recombinant Protein
H00055662-P01
Species: Hu
Applications: WB, ELISA, PA
FIH-1/HIF-1AN Recombinant Pro ...
FIH-1/HIF-1AN Recombinant Protein
NBC1-22596
Species: Hu
Applications: PAGE
Host: Human
RNAi
FIH-1/HIF-1AN RNAi
FIH-1/HIF-1AN RNAi
H00055662-R01
Species: Hu

Description

Factor Inhibiting HIF1 (FIH) protein facilitates repression of HIF-1 transcriptional activity by binding to VHL, which acts as a transcriptional corepressor. VHL inhibits HIF-1 alpha transactivation function by recruiting histone deacetylases. Involvement of VHL in association with FIH provides a unifying mechanism for the modulation of HIF-1 alpha protein stabilization and transcriptional activation in response to changes in cellular oxygen concentration.

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Human
Human
Human
Product By Gene ID 55662
Alternate Names
  • EC 1.14.11.16
  • Factor inhibiting HIF-1
  • peptide-aspartate beta-dioxygenase
  • FLJ22027
  • hypoxia-inducible factor 1-alpha inhibitor
  • FLJ20615
  • factor inhibiting HIF1
  • DKFZp762F1811
  • FIH1FIH-1
  • Hypoxia-inducible factor asparagine hydroxylase
  • hypoxia inducible factor 1, alpha subunit inhibitor

Research Areas for FIH-1/HIF-1AN

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Chromatin Research
Hypoxia
Transcription Factors and Regulators

PTMs for FIH-1/HIF-1AN

Learn more about PTMs related to FIH-1/HIF-1AN.

Hydroxylation
Ubiquitination
Phosphorylation
Methylation
Acetylation

Bioinformatics Tool for FIH-1/HIF-1AN

Discover related pathways, diseases and genes to FIH-1/HIF-1AN. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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