Fibrillin 1 Antibody

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Western Blot: Fibrillin 1 Antibody [NBP2-16493] - Sample (30 ug of whole cell lysate) A: Hela 5% SDS PAGE gel, diluted at 1:1000.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, CaSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
2 mg/ml

Order Details

Fibrillin 1 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the C-terminus region of human Fibrillin 1. The exact sequence is proprietary.
Localization
Secreted; extracellular space; extracellular matrix
Predicted Species
Mouse (92%), Rat (90%), Porcine (95%), Canine (92%), Bovine (95%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
FBN1
Purity
Protein A purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
312 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 40% Glycerol
Preservative
0.01% Thimerosal
Concentration
2 mg/ml
Purity
Protein A purified

Alternate Names for Fibrillin 1 Antibody

  • FBN
  • fibrillin 1 (Marfan syndrome)
  • fibrillin 1
  • fibrillin 15
  • fibrillin-1
  • MASS
  • MFS1
  • OCTD
  • SGS
  • SSKS
  • WMS

Background

This gene encodes a member of the fibrillin family. The encoded protein is a large, extracellular matrix glycoprotein that serve as a structural component of 10-12 nm calcium-binding microfibrils. These microfibrils provide force bearing structural support in elastic and nonelastic connective tissue throughout the body. Mutations in this gene are associated with Marfan syndrome, isolated ectopia lentis, autosomal dominant Weill-Marchesani syndrome, MASS syndrome, and Shprintzen-Goldberg craniosynostosis syndrome. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for Fibrillin 1 Antibody (NBP2-16493). (Showing 1 - 1 of 1 FAQ).

  1. Hi - I have been looking at the fibrillin1 antibodies on your website. You indicate that some may be suitable for canine tissue on the front page http://www.novusbio.com/primary-antibodies/fibrillin-1. could you let me know which of the 10 antibodies is the most suitable for canine.
    • We have unfortuantely not tested any of our products in canine samples. If you would like to try one of our product with canine samples, you would qualify for our Innovator's Reward Program. In exchange for a review of our product in an untested application or species, we would issue you a credit voucher for the purchase price. If you would like us to check the homology of a certain product against the canine sequence, just contact our technical support department at technical@novusbio.com.

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol FBN1
Uniprot