Western Blot: eIF4G1 [p Ser1232] Antibody [NBP1-04965] - Western blot analysis of extracts from 293 cell using eIF4G Antibody (Lane 1 and 2) and eIF4G (phospho-Ser1232) antibody.
Immunohistochemistry: eIF4G1 [p Ser1232] Antibody [NBP1-04965] - eIF4G1 [p Ser1232] Antibody Immunohistochemical analysis of paraffin-embedded human lung carcinoma tissue using eIF4G (phospho- Ser1232) antibody
Western Blot: eIF4G1 [p Ser1232] Antibody [NBP1-04965] - Kinetics of eIF4G1 (s1232) phosphorylation in response to PKC/Ras/Erk activation by Sapintoxin D. Photo courtesy of a product review by the Gromeier Lab at Duke ...read more
Western Blot: eIF4G1 [p Ser1232] Antibody [NBP1-04965] - HT29 cells untreated or treated with Anisomycin.
220 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
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eIF4G1 (eukaryotic translation Initiation Factor 4 Gamma 1) is a component of the protein complex eIF-4 which is involved in the recognition of the mRNA cap ATP-dependent unwinding of the 5'-terminal secondary structure and recruitment of mRNA to the ribosome. eIF4G plays a critical role in protein expression and is at the center of a complex regulatory network. Together with the cap-binding protein eIF4E, it recruits the small ribosomal subunit to the 5'-end of mRNA and promotes the assembly of a functional translation initiation complex which scans along the mRNA to the translation start codon. Human eIF4G contains three consecutive HEAT domains, as well as long unstructured regions involved in multiple protein-protein interactions. The interactions of eIF4G1 with other factors are largely unknown.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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