Immunocytochemistry/ Immunofluorescence: DNMT3A Antibody [NBP1-85961] - Immunofluorescent staining of human cell line A-431 shows localization to nucleoplasm.
Orthogonal Strategies: Immunohistochemistry-Paraffin: DNMT3A Antibody [NBP1-85961] - Staining in human lymph node and liver tissues. Corresponding DNMT3A RNA-seq data are presented for the same tissues.
Immunohistochemistry-Paraffin: DNMT3A Antibody [NBP1-85961] - Staining of human lymph node shows strong nuclear positivity.
Immunohistochemistry-Paraffin: DNMT3A Antibody [NBP1-85961] - Staining of human endometrium shows strong nuclear positivity.
Immunohistochemistry-Paraffin: DNMT3A Antibody [NBP1-85961] - Staining of human kidney shows nuclear positivity in cells in glomeruli and tubular cells.
Immunohistochemistry-Paraffin: DNMT3A Antibody [NBP1-85961] - Staining of human liver shows strong nuclear positivity in hepatocytes.
This antibody was developed against Recombinant Protein corresponding to amino acids: LPEASRAVENGCCTPKEGRGAPAEAGKEQKETNIESMKMEGSRGRLRGGLGWESSLRQRPMPRLTFQAGDPYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQGPGESQKVEE
Specificity of human, mouse, rat DNMT3A antibody verified on a Protein Array containing target protein plus 383 other non-specific proteins.
Rat (91%). Backed by our 100% Guarantee.
Immunogen affinity purified
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The role of DNMT3A in development Epigenetics is the study of heritable change in gene activity despite alteration of the hosts DNA sequence. Change in gene activity done independently of the DNA sequence is achieved by way of histone and DNA methylation. Gene silencing in DNA ... Read full blog post.
Go Ahead! Make My DNA DNA methylation plays a critical role the long-term silencing of transcription and is essential for processes such as embryonic development, germline differentiation, and tissue maturation. Dnmt3a is a member of the C5-methyltransferase family that re... Read full blog post.
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