DGAT1 Antibody (23GB5155)

• Reactivity: Hu
• Applications: WB, Flow, Mycoplasma
• Clone: 23GB5155
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

DGAT1 Antibody (23GB5155) Summary

• Immunogen: A synthesized peptide derived from human DGAT1 (Uniprot: O75907)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: DGAT1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Knockdown Validated
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for DGAT1 Antibody (23GB5155)

• ACAT-related gene product 1
• AGRP1
• ARAT
• ARGP1
• ARGP1acyl coenzyme A:cholesterol acyltransferase related gene 1
• DGAT
• DGAT1
• DGATACAT related gene product 1
• diacylglycerol O-acyltransferase 1
• diacylglycerol O-acyltransferase homolog 1 (mouse)
• diacylglycerol O-acyltransferase homolog 1
• DIAR7
• Diglyceride acyltransferase
• EC 2.3.1
• EC 2.3.1.20

Background

Diglyceride acyltransferase (DGAT) is a membrane-bound Sterol o-acyltransferase subfamily member. DGAT1 is a microsomal enzyme that assists in the synthesis of fatty acids into triglycerides. Specifically, it catalyzes the terminal step in triacylglycerol synthesis, using diacylglycerol (DAG) and fatty acyl CoA as substrates.

DGAT plays a fundamental role in the metabolism of cellular diacylglycerol and is important in higher eukaryotes for physiologic processes involving triacylglycerol metabolism such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation. DGAT1 is involved in fat absorption in the intestine and in basal level triglyceride synthesis in adipose tissue, where it is more highly expressed.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: DGAT1