Western blotting (0.5-4 ug/ml). However, the optimal conditions should be determined individually. The antibody recognizes 28 kDa of Dectin-1 from samples of human origins. A ~16 kDa monomeric form and a 43 kDa glycoprotein can also be detected. Reactivity to other species has not been tested.
27.6 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Read 2 Reviews rated 4.5 using NBP1-45514 in the following application:
This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. The encoded glycoprotein is a small type II membrane receptor with an extracellular C-type lectin-like domain fold and a cytoplasmic domain with an immunoreceptor tyrosine-based activation motif. It functions as a pattern-recognition receptor that recognizes a variety of beta-1,3-linked and beta-1,6-linked glucans from fungi and plants, and in this way plays a role in innate immune response. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene is closely linked to other CTL/CTLD superfamily members on chromosome 12p13 in the natural killer gene complex region.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for Dectin-1/CLEC7A Antibody (NBP1-45514). (Showing 1 - 1 of 1 FAQ).
I am looking for a human dectin-1 and 2 for western blot. How can I know if it works? Do you have any references from the literature that confirm your products? If yes-I'll be happy to read few articles who used your dectin-1 and it worked.
Unfortunately, to the best of our knowledge, our dectin antibodies have not been cited in literature yet, and for the peace of your mind, my suggestion to you would be to make your decision based upon the validation images shown on datasheets. You may find our Dectin 1 and Dectin 2 antibodies suitable for WB application using these links. We stand by the quality of our products and all our products are 100% guaranteed. We are always there to help in case you face any trouble in generating your desired outcome out of the use of our products. Please let me know if I can help you with any other queries.
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