CTLA-4 Antibody (1B8) [PE/Cy5.5]

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Product Details

Summary
Reactivity MuSpecies Glossary
Applications Flow
Clone
1B8
Clonality
Monoclonal
Host
Armenian Hamster
Conjugate
PE/Cy5.5

Order Details

CTLA-4 Antibody (1B8) [PE/Cy5.5] Summary

Immunogen
Extracellular portion of mouse CD152 fused to a mouse IgG2a.
Specificity
This antibody recognises mouse CD152, commonly known as CTLA-4 (cytotoxic T-lymphocyte protein 4), a structural homolog for CD28. CD152 binds the same ligands as CD28, namely CD80 (B7.1) and CD86 (B7.2), but with much higher affinity. However, while binding of CD28 enhances T cell function, binding of CD152 inhibits it. CD152 is not detected on naive T-cells and is induced upon T-cell activation.
Isotype
IgG
Clonality
Monoclonal
Host
Armenian Hamster
Gene
CTLA4
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry
Application Notes
Optimal dilution of this antibody should be experimentally determined. For optimal results using our Tandem dyes, please avoid prolonged exposure to light or extreme temperature fluctuations. These can lead to irreversible degradation or decoupling. When staining intracellular targets, specific attention to the fixation and permeabilization steps in your flow protocol may be required. Please contact our technical support team at technical@novusbio.com if you have any questions.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark. Do not freeze.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for CTLA-4 Antibody (1B8) [PE/Cy5.5]

  • CD
  • CD152 antigen
  • CD152
  • CD152IDDM12
  • CD28
  • celiac disease 3
  • CELIAC3
  • CTLA4
  • CTLA-4
  • cytotoxic T-lymphocyte antigen 4
  • cytotoxic T-lymphocyte protein 4
  • Cytotoxic T-lymphocyte-associated antigen 4
  • cytotoxic T-lymphocyte-associated protein 4
  • cytotoxic T-lymphocyte-associated serine esterase-4
  • GRD4
  • GSE
  • ICOS
  • ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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FAQs for CTLA-4 Antibody (NBP1-41000PECY55) (0)

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Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP1-41000AF350
Alexa Fluor 405 NBP1-41000AF405
Alexa Fluor 488 NBP1-41000AF488
Alexa Fluor 532 NBP1-41000AF532
Alexa Fluor 594 NBP1-41000AF594
Alexa Fluor 647 NBP1-41000AF647
Alexa Fluor 700 NBP1-41000AF700
Alexa Fluor 750 NBP1-41000AF750
Allophycocyanin NBP1-41000APC
Allophycocyanin/Cy7 NBP1-41000APCCY7
Biotin NBP1-41000B
DyLight 350 NBP1-41000UV
DyLight 405 NBP1-41000V
DyLight 488 NBP1-41000G
DyLight 550 NBP1-41000R
DyLight 594 NBP1-41000DL594
DyLight 650 NBP1-41000C
DyLight 680 NBP1-41000FR
DyLight 755 NBP1-41000IR
FITC NBP1-41000F
HRP NBP1-41000H
Janelia Fluor 549 NBP1-41000JF549
Janelia Fluor 646 NBP1-41000JF646
PE NBP1-41000PE
PE/Atto594 NBP1-41000PEATT594
PE/Cy5.5 NBP1-41000PECY55
PE/Cy7 NBP1-41000PECY7
PerCP NBP1-41000PCP

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Blogs on CTLA-4.

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Here at Bio-Techne we always look forward to the annual announcements of winners of the highly coveted Nobel Prize – the greatest award in science. How can you go about predicting which scientists might be in line for a life-changing phone-call fro...  Read full blog post.

CD86 - I work in tandem with CD80
CD86 belongs to the immunoglobulin superfamily of proteins that drive innate and adaptive immune responses. It is an 80kD co-stimulatory molecule for the priming and activation of naive and memory T-cells, respectively. CD86 is expressed on activated...  Read full blog post.

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Bioinformatics

Gene Symbol CTLA4