CTLA-4 Products

Antibodies
CTLA-4 Antibody [Unconjugated ...
CTLA-4 Antibody [Unconjugated]
AF-386-PB
Species: Hu
Applications: WB, Flow, ICC
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
CTLA-4 Antibody (BNI3)
CTLA-4 Antibody (BNI3)
NB100-64849
Species: Hu
Applications: Flow, IHC, IHC-Fr, IP
Host: Mouse Monoclonal
Antibody Pairs
CTLA-4 Antibody Pair
CTLA-4 Antibody Pair
H00001493-AP41
Species: Hu
Applications: S-ELISA
ELISA Kits
CTLA-4 ELISA Kit
CTLA-4 ELISA Kit
NBP1-91268
Species: Hu
Applications: ELISA
CTLA-4 ELISA Kit [Biotin]
CTLA-4 ELISA Kit [Biotin]
KA0165
Species: Hu
Lysates
CTLA-4 Overexpression Lysate ...
CTLA-4 Overexpression Lysate (Native)
NBP2-07774
Proteins
CTLA-4 Recombinant Protein
CTLA-4 Recombinant Protein
NBP2-22987
Species: Hu
Applications: PAGE
CTLA-4 Recombinant Protein
CTLA-4 Recombinant Protein
NBP2-52321
Species: Mu
Applications: PAGE
CTLA-4 Recombinant Protein
CTLA-4 Recombinant Protein
NBP2-52334
Species: Hu
Applications: PAGE
RNAi
CTLA-4 RNAi
CTLA-4 RNAi
H00001493-R05
Species: Hu
Applications: RNAi, RNAi SP
CTLA-4 RNAi
CTLA-4 RNAi
H00001493-R04
Species: Hu
Applications: RNAi, RNAi SP
CTLA-4 RNAi
CTLA-4 RNAi
H00001493-R01
Species: Hu
Applications: RNAi, RNAi SP

Description

The lymphocyte surface antigen CD152, also known as CTLA-4, is related to the co-stimulatory molecule CD28, and both molecules share common B7 family counter-receptors. (1-4) However CD152 is thought to be a negative regulator of T cell activation (1-3) and may play a role in apoptotic control of T cells. CD152 exists as a 69 kDa homodimer1, and is relatively conserved among humans, mice and chickens. (2)

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Human
Mouse
Product By Gene ID 1493
Alternate Names
  • CD152 antigen
  • CELIAC3
  • ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4
  • CTLA-4
  • cytotoxic T-lymphocyte-associated serine esterase-4
  • Cytotoxic T-lymphocyte-associated antigen 4
  • cytotoxic T-lymphocyte protein 4
  • celiac disease 3
  • cytotoxic T-lymphocyte antigen 4
  • ICOS
  • GSE
  • CD28
  • CD
  • CD152IDDM12
  • GRD4
  • cytotoxic T-lymphocyte-associated protein 4

Research Areas for CTLA-4

Find related products by research area and learn more about each of the different research areas below.

Signal Transduction

Bioinformatics Tool for CTLA-4

Discover related pathways, diseases and genes to CTLA-4. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related CTLA-4 Blog Posts

Check out the latest blog posts on CTLA-4.
CD86 - I work in tandem with CD80
CD86 belongs to the immunoglobulin superfamily of proteins that drive innate and adaptive immune responses. It is an 80kD co-stimulatory molecule for the priming and activation of naive and memory T-cells, respectively. CD86 is expressed on activated...    Read more.
Read more CTLA-4 related blogs.