CHD9 Antibody

Western Blot: CHD9 Antibody [NB100-60419] - Detection of Human CHD9/CReMM on HeLa whole cell lysate using NB100-60419.

• Reactivity: Hu, Mu
• Applications: WB, IB, IP
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Concentration: 1.0 mg/ml

CHD9 Antibody Summary

• Immunogen: The immunogen recognized by this antibody maps to a region between residue 25 and 75 of human chromodomain helicase DNA binding protein 9 (chromatin-related mesenchymal modulator) using the numbering given in entry AAQ24287.1 (GeneID 80205).
• Predicted Species: Mouse (100%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: CHD9
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunoblotting
  • Immunoprecipitation 2-5 ug/mg lysate
  • Western Blot 1:1000-1:5000
• Application Notes: Use in Immunoblotting reported in scientific literature (PMID 28381557).

Packaging, Storage & Formulations

• Storage: Store at 4C. Do not freeze.
• Buffer: Tris-Citrate/Phosphate (pH 7.0 - 8.0)
• Preservative: 0.09% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for CHD9 Antibody

• AD013
• ATP-dependent helicase CHD9
• BC022889
• CHD-9
• chromatin remodeling factor CHROM1
• Chromatin-related mesenchymal modulator
• Chromatin-remodeling factor CHROM1
• chromodomain helicase DNA binding protein 9
• chromodomain-helicase-DNA-binding protein 9
• ciprofibrate bound protein p240
• CReMM
• EC 3.6.1
• EC 3.6.4.12
• FLJ12178
• KIAA0308
• KISH2
• Kismet homolog 2
• Peroxisomal proliferator-activated receptor A-interacting complex 320 kDaprotein
• PPAR{gamma}-interacting cofactor 320 kDa
• PPAR-alpha-interacting complex protein 320 kDa
• PRIC320
• proteinx0008

Background

CHD9/CReMM is a member of the CHD (chromodomain-helicase-DNA-binding) family of proteins that interacts with nucleosomes and plays a role in chromatin remodeling to modulate transcription. The members of the CHD family of proteins possess 3 common structural and functional domains: a chromodomain (chromatin organization modifier), an SNF2-like helicase/ATPase domain, and a C-terminal DNA-binding domain. CHD9/CReMM is thought to play a role in development due to its role in tissue-specific gene transcription. CHD9/CReMM also functions as a PPARA transcriptional coactivator. Alternate names for CHD9/CreMM include chromodomain-helicase-DNA-binding protein 9, ATP-dependent helicase CHD9, chromatin-related mesenchymal modulator, chromatin-remodeling factor CHROM1, PPARA-interacting complex 320 kDa protein, kismet homolog 2, KIAA0308, KISH2, AD013, and PRIC320.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for CHD9 Antibody (NB100-60419)(1)

Publication using NB100-60419

• Lee BH, Stallcup MR. Glucocorticoid Receptor Binding to Chromatin is Selectively Controlled by Coregulator Hic-5 and Chromatin Remodeling Enzymes. J. Biol. Chem. 2017-04-05 [PMID: 28381557] (IB, Human)

Bioinformatics

• Gene Symbol: CHD9
• Entrez:
  • 80205(Human)
• Uniprot:
  • Q3L8U1(Human)