Western Blot: CHD4 Antibody [NB100-57521] - Detection of Human and Mouse CHD4/Mi2 beta on HeLa whole cell lysate using Nb100-57521. CHD4/Mi2 beta was also immunoprecipitated by Nb100-57520 and another anti-CHD4/Mi2 beta.
The immunogen recognized by this antibody maps to a region between residue 1625 and 1675 of human chromodomain helicase DNA binding protein 4 (Mi2 autoantigen 218 kDa protein) using the numbering given in entry NP_001264.2 (GeneID 1108).
Immunogen affinity purified
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CHD4/Mi2beta is a helicase component of the nucleosome remodeling and deacetylase (NuRD) complex that functions to remodel chromatin and repress transcription. Outside of the NuRD complex, CHD4/Mi2beta can function as an activator of transcription in association with p300 histone acetyltransferase. Alternate names for CHD4/Mi2beta include chromodomain-helicase-DNA-binding protein 4, CHD-4, ATP-dependent helicase CHD4, Mi-2 autoantigen 218 kDa protein, Mi2-beta, Mi-2b, and DKFZp686E06161.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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