CDC25C Antibody (461908) [DyLight 755]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: 461908
• Clonality: Monoclonal
• Host: Rat
• Conjugate: DyLight 755

CDC25C Antibody (461908) [DyLight 755] Summary

• Immunogen: E. coli-derived recombinant human CDC25C
  Ser2-Pro473
  Accession # P30307
• Specificity: Detects human, mouse and rat CDC25C in Western blots. In Western blots, no cross-reactivity with recombinant human (rh) CDC25A or rhCDC25B is observed.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Rat
• Gene: CDC25C
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for CDC25C Antibody (461908) [DyLight 755]

• CDC 25
• CDC25
• CDC25C
• cell division cycle 25 homolog C (S. cerevisiae)
• cell division cycle 25 homolog C (S. pombe)
• cell division cycle 25C
• Dual specificity phosphatase Cdc25C
• EC 3.1.3.48
• mitosis inducer CDC25
• M-phase inducer phosphatase 3
• phosphotyrosine phosphatase

Background

Cdc25C is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: CDC25C